Literature DB >> 9177342

Functional rafts in cell membranes.

K Simons, E Ikonen.   

Abstract

A new aspect of cell membrane structure is presented, based on the dynamic clustering of sphingolipids and cholesterol to form rafts that move within the fluid bilayer. It is proposed that these rafts function as platforms for the attachment of proteins when membranes are moved around inside the cell and during signal transduction.

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Year:  1997        PMID: 9177342     DOI: 10.1038/42408

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  2000 in total

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7.  Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1).

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Review 9.  Selective targeting of glutamate receptors in neurons.

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Journal:  Mol Neurobiol       Date:  2000 Feb-Apr       Impact factor: 5.590

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