| Literature DB >> 24395427 |
A Leferink1, D Schipper, E Arts, E Vrij, N Rivron, M Karperien, K Mittmann, C van Blitterswijk, L Moroni, R Truckenmüller.
Abstract
A material-based bottom-up approach is proposed towards an assembly of cells and engineered micro-objects at the macroscale. We show how shape, size and wettability of engineered micro-objects play an important role in the behavior of cells on these objects. This approach can, among other applications, be used as a tool to engineer complex 3D tissues of clinically relevant size.Keywords: biofabrication; bottom-up tissue engineering; cell aggregates; human mesenchymal stromal cells; micro-objects
Mesh:
Year: 2014 PMID: 24395427 DOI: 10.1002/adma.201304539
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849