Literature DB >> 24395237

SmeOP-TolCSm efflux pump contributes to the multidrug resistance of Stenotrophomonas maltophilia.

Cheng-Wen Lin1, Yi-Wei Huang, Rouh-Mei Hu, Tsuey-Ching Yang.   

Abstract

A five-gene cluster, tolCSm-pcm-smeRo-smeO-smeP, of Stenotrophomonas maltophilia was characterized. The presence of smeOP and smeRo-pcm-tolCSm operons was verified by reverse transcription (RT)-PCR. Both operons were negatively regulated by the TetR-type transcriptional regulator SmeRo, as demonstrated by quantitative RT-PCR and a promoter-fusion assay. SmeO and SmeP were associated with TolCSm (the TolC protein of S. maltophilia) for the assembly of a resistance-nodulation-cell-division (RND)-type pump. The compounds extruded by SmeOP-TolCSm mainly included nalidixic acid, doxycycline, amikacin, gentamicin, erythromycin, leucomycin, carbonyl cyanide 3-chlorophenylhydrazone, crystal violet, sodium dodecyl sulfate, and tetrachlorosalicylanilide.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24395237      PMCID： PMC4023765          DOI： 10.1128/AAC.01974-13

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

Review 1.  Molecular properties of bacterial multidrug transporters.

Authors:  M Putman; H W van Veen; W N Konings
Journal:  Microbiol Mol Biol Rev       Date:  2000-12       Impact factor: 11.056

2.  Contribution of resistance-nodulation-division efflux pump operon smeU1-V-W-U2-X to multidrug resistance of Stenotrophomonas maltophilia.

Authors:  Chao-Hsien Chen; Chiang-Ching Huang; Tsao-Chuen Chung; Rouh-Mei Hu; Yi-Wei Huang; Tsuey-Ching Yang
Journal:  Antimicrob Agents Chemother       Date:  2011-09-19       Impact factor: 5.191

3.  Coordinate hyperproduction of SmeZ and SmeJK efflux pumps extends drug resistance in Stenotrophomonas maltophilia.

Authors:  Virginia C Gould; Aki Okazaki; Matthew B Avison
Journal:  Antimicrob Agents Chemother       Date:  2012-11-12       Impact factor: 5.191

4.  AmpN-AmpG operon is essential for expression of L1 and L2 beta-lactamases in Stenotrophomonas maltophilia.

Authors:  Yi-Wei Huang; Cheng-Wen Lin; Rouh-Mei Hu; Yu-Tzu Lin; Tung-Ching Chung; Tsuey-Ching Yang
Journal:  Antimicrob Agents Chemother       Date:  2010-04-12       Impact factor: 5.191

5.  SmeC, an outer membrane multidrug efflux protein of Stenotrophomonas maltophilia.

Authors:  Xian-Zhi Li; Li Zhang; Keith Poole
Journal:  Antimicrob Agents Chemother       Date:  2002-02       Impact factor: 5.191

6.  Role of the pcm-tolCsm operon in the multidrug resistance of Stenotrophomonas maltophilia.

Authors:  Yi-Wei Huang; Rouh-Mei Hu; Tsuey-Ching Yang
Journal:  J Antimicrob Chemother       Date:  2013-04-29       Impact factor: 5.790

7.  A model of a transmembrane drug-efflux pump from Gram-negative bacteria.

Authors:  Juan Fernandez-Recio; Fabien Walas; Luca Federici; J Venkatesh Pratap; Vassiliy N Bavro; Ricardo Nunez Miguel; Kenji Mizuguchi; Ben Luisi
Journal:  FEBS Lett       Date:  2004-12-03       Impact factor: 4.124

8.  Cloning and characterization of SmeDEF, a novel multidrug efflux pump from Stenotrophomonas maltophilia.

Authors:  A Alonso; J L Martínez
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

9.  Mechanism and Function of the Outer Membrane Channel TolC in Multidrug Resistance and Physiology of Enterobacteria.

Authors:  Helen I Zgurskaya; Ganesh Krishnamoorthy; Abigail Ntreh; Shuo Lu
Journal:  Front Microbiol       Date:  2011-09-16       Impact factor: 5.640

10.  The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants.

Authors:  Lisa C Crossman; Virginia C Gould; J Maxwell Dow; Georgios S Vernikos; Aki Okazaki; Mohammed Sebaihia; David Saunders; Claire Arrowsmith; Tim Carver; Nicholas Peters; Ellen Adlem; Arnaud Kerhornou; Angela Lord; Lee Murphy; Katharine Seeger; Robert Squares; Simon Rutter; Michael A Quail; Mari-Adele Rajandream; David Harris; Carol Churcher; Stephen D Bentley; Julian Parkhill; Nicholas R Thomson; Matthew B Avison
Journal:  Genome Biol       Date:  2008-04-17       Impact factor: 13.583
  10 in total
  23 in total

1.  Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia.

Authors:  Yi-Wei Huang; Cheng-Wen Lin; Hsiao-Chen Ning; Yi-Tsung Lin; Yi-Chih Chang; Tsuey-Ching Yang
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

Review 2.  The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.

Authors:  Xian-Zhi Li; Patrick Plésiat; Hiroshi Nikaido
Journal:  Clin Microbiol Rev       Date:  2015-04       Impact factor: 26.132

3.  Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria.

Authors:  Ilyas Alav; Jessica Kobylka; Miriam S Kuth; Klaas M Pos; Martin Picard; Jessica M A Blair; Vassiliy N Bavro
Journal:  Chem Rev       Date:  2021-04-28       Impact factor: 60.622

4.  Vitamin K3 Induces the Expression of the Stenotrophomonas maltophilia SmeVWX Multidrug Efflux Pump.

Authors:  P Blanco; F Corona; M B Sánchez; J L Martínez
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

5.  AbuO, a TolC-like outer membrane protein of Acinetobacter baumannii, is involved in antimicrobial and oxidative stress resistance.

Authors:  Vijaya Bharathi Srinivasan; Vasanth Vaidyanathan; Govindan Rajamohan
Journal:  Antimicrob Agents Chemother       Date:  2014-12-15       Impact factor: 5.191

6.  The SmeYZ efflux pump of Stenotrophomonas maltophilia contributes to drug resistance, virulence-related characteristics, and virulence in mice.

Authors:  Yi-Tsung Lin; Yi-Wei Huang; Shiang-Jiuun Chen; Chia-Wei Chang; Tsuey-Ching Yang
Journal:  Antimicrob Agents Chemother       Date:  2015-04-27       Impact factor: 5.191

7.  Inactivation of Lytic Transglycosylases Increases Susceptibility to Aminoglycosides and Macrolides by Altering the Outer Membrane Permeability of Stenotrophomonas maltophilia.

Authors:  Chao-Jung Wu; Yi-Wei Huang; Yi-Tsung Lin; Tsuey-Ching Yang
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

8.  Overexpression of the Efflux Pumps SmeVWX and SmeDEF Is a Major Cause of Resistance to Co-trimoxazole in Stenotrophomonas maltophilia.

Authors:  María Blanca Sánchez; José Luis Martínez
Journal:  Antimicrob Agents Chemother       Date:  2018-05-25       Impact factor: 5.191

9.  Mutations in Ribosomal Protein RplA or Treatment with Ribosomal Acting Antibiotics Activates Production of Aminoglycoside Efflux Pump SmeYZ in Stenotrophomonas maltophilia.

Authors:  Karina Calvopiña; Punyawee Dulyayangkul; Matthew B Avison
Journal:  Antimicrob Agents Chemother       Date:  2020-01-27       Impact factor: 5.191

10.  Stenotrophomonas maltophilia produces an EntC-dependent catecholate siderophore that is distinct from enterobactin.

Authors:  Megan Y Nas; Nicholas P Cianciotto
Journal:  Microbiology       Date:  2017-10-06       Impact factor: 2.777
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.