| Literature DB >> 24393943 |
Tomohisa Egawa1, Yusuke Okubo, Takeshi Kemmochi, Takayuki Mori, Shinji Sato, Shin Nishiya, Koki Mihara, Yasuhiro Ito, Hiroyuki Makino, Atsushi Nagashima.
Abstract
A 70-year-old woman was diagnosed as having advanced lower thoracic esophageal cancer with abdominal lymph node metastases(T3N1M0, Stage III). After administering 2 courses of neoadjuvant chemotherapy with 5-fluorouracil(5- FU)( 800 mg/m2)and cisplatin(80 mg/m2), we performed curative surgery with D2 lymph node dissection. The patient could not receive adjuvant chemotherapy because of her poor performance status. After curative surgery, liver metastasis appeared in segment 8. The liver metastasis(S8)was treated with stereotactic body radiation therapy(SBRT)( 60 Gy/3 Fr). After SBRT, we administered systemic chemotherapy with docetaxel and nedaplatin as second-line chemotherapy. The patient had no recurrence for 12 months after SBRT. SBRT exhibited an excellent local therapeutic effect without any serious complications, suggesting that it is an effective treatment for liver metastasis from esophageal cancer.Entities:
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Year: 2013 PMID: 24393943
Source DB: PubMed Journal: Gan To Kagaku Ryoho ISSN: 0385-0684