Literature DB >> 24392466

An effective programme to systematic diabetic retinopathy screening in order to reduce diabetic retinopathy blindness.

Evangelia Papavasileiou1, Dimitrios Dereklis, Panayiotis Oikonomidis, Andre Grixti, Balakrishna Vineeth Kumar, Som Prasad.   

Abstract

The number of people identified with diabetes in England increased by nearly 5% during 2011-2012 to well over 2.5 million. During 2011-2012 the NHS Diabetic Eye Screening Programme screened more than 1.9 million people. In general, the UK is doing very well with its DR screening targets. It is a world leader in diabetic retinopathy screening, having offered 85.7% of eligible diabetic patients the screening programme. However, the target is 100% and efforts are still being made to improve screening locally. Our aim is to evaluate the prevalence of sight-threatening diabetic retinopathy (STDR) (proliferative retinopathy or maculopathy), the number of patients needing laser treatment or vitrectomy and registered blind in the last 12 months in a defined population. We did a twelve-month retrospective database review at the Systematic Diabetic Retinopathy Screening Service at Wirral University Hospital Trust, United Kingdom. The effectiveness of different screening modalities has been widely investigated. UK studies show sensitivity levels for the detection of sight-threatening diabetic retinopathy of 41%-67% for general practitioners, 48%-82% for optometrists, 65% for ophthalmologists, and 27%-67% for diabetologists and hospital physicians using direct ophthalmoscopy. Sensitivity for the detection of referable retinopathy by optometrists have been found to be 77%-100%, with specificity of 94%-100%. Photographic methods currently use digital images with subsequent grading by trained individuals. Sensitivity for the detection of sight-threatening diabetic retinopathy have been found 87%-100% for a variety of trained personnel reading mydriatic 45° retinal photographs, with specificities of 83%-96%. The British Diabetic Association (Diabetes UK) has established standard values for any diabetic retinopathy screening programme of at least 80% sensitivity and 95% specificity. We used descriptive analyses to characterise the study population and patterns of diabetic retinopathy, and used t tests and χ(2) tests to explore differences between patients without any retinopathy and those who developed any, background, or referable retinopathy. Parametric survival analysis with covariates identified those factors associated with the development of referable retinopathy. The presence of diabetic retinopathy was determined after each screening event during the study period. Although intended to occur annually, screening took place at variable times during the one year period. Of known diabetics in a total population 325.000, 84% accessed screening and 15.196 (4.7%) were screened. 748 were referred with referable retinopathy. 16% of the patients needed laser treatment for the first time, 30 patients needed vitrectomy, and 16 were registered blind. To evaluate the effectiveness of diabetic retinopathy screening (DRS) service we did a retrospective comparative analysis of 2 year DRS data in Wirral (2010-2012). An increase of 6.8% in the number of diabetics was noted over the last 12 months compared to the previous period. Referable retinopathy decreased from 5.6% for 2010-2011 to 4.94% during the same period in 2011-2012. In particular, the incidence of proliferative retinopathy (R3) has dropped from 0.7% last year to 0.52% this year. STDR has significant impact on ophthalmic services, but a well-implemented program provides timely treatment, reducing the need for vitrectomy and blind registration and serving as a benchmark to plan service delivery in a similar population.

Entities:  

Year:  2014        PMID: 24392466

Source DB:  PubMed          Journal:  Hell J Nucl Med        ISSN: 1790-5427            Impact factor:   1.102


  10 in total

Review 1.  Oxidative stress and diabetic retinopathy: development and treatment.

Authors:  G D Calderon; O H Juarez; G E Hernandez; S M Punzo; Z D De la Cruz
Journal:  Eye (Lond)       Date:  2017-04-28       Impact factor: 3.775

2.  Influence of comorbidities on the implementation of the fundus examination in patients with newly diagnosed type 2 diabetes.

Authors:  Taichi Kawamura; Izumi Sato; Hiroshi Tamura; Yoko M Nakao; Koji Kawakami
Journal:  Jpn J Ophthalmol       Date:  2017-12-05       Impact factor: 2.447

Review 3.  Mechanisms involved in the development of diabetic retinopathy induced by oxidative stress.

Authors:  David Calderón Guzman; Hugo Juárez Olguín; Ernestina Hernández García; Armando Valenzuela Peraza; Diego Zamora de la Cruz; Monica Punzo Soto
Journal:  Redox Rep       Date:  2016-07-15       Impact factor: 4.412

Review 4.  The Role of MicroRNAs in Diabetic Complications-Special Emphasis on Wound Healing.

Authors:  João Moura; Elisabet Børsheim; Eugenia Carvalho
Journal:  Genes (Basel)       Date:  2014-09-29       Impact factor: 4.096

Review 5.  Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine.

Authors:  Suzanne Hagan; Eilidh Martin; Amalia Enríquez-de-Salamanca
Journal:  EPMA J       Date:  2016-07-13       Impact factor: 6.543

6.  The Nonmydriatic Fundus Camera in Diabetic Retinopathy Screening: A Cost-Effective Study with Evaluation for Future Large-Scale Application.

Authors:  Giuseppe Scarpa; Francesca Urban; Stela Vujosevic; Michele Tessarin; Giovanni Gallo; Annalisa Visentin; Emanuela Foglia; Lucrezia Ferrario; Edoardo Midena
Journal:  J Ophthalmol       Date:  2016-11-03       Impact factor: 1.909

Review 7.  Prevalence of diabetic retinopathy in Pakistan; A systematic review.

Authors:  Seema N Mumtaz; Muhammad Faisal Fahim; Muhammad Arslan; Sikander Ali Shaikh; Umer Kazi; Muhammad Saleh Memon
Journal:  Pak J Med Sci       Date:  2018 Mar-Apr       Impact factor: 1.088

8.  Identification of risk factors for targeted diabetic retinopathy screening to urgently decrease the rate of blindness in people with diabetes in India.

Authors:  Sagnik Sen; Kim Ramasamy; T P Vignesh; Naresh B Kannan; Sobha Sivaprasad; Ramachandran Rajalakshmi; Rajiv Raman; Viswanathan Mohan; Taraprasad Das; Iswarya Mani
Journal:  Indian J Ophthalmol       Date:  2021-11       Impact factor: 1.848

Review 9.  Telemedicine in diabetic retinopathy screening in India.

Authors:  Kim Ramasamy; Chitaranjan Mishra; Naresh B Kannan; P Namperumalsamy; Sagnik Sen
Journal:  Indian J Ophthalmol       Date:  2021-11       Impact factor: 1.848

10.  SCREENING FOR DIABETIC RETINOPATHY - A TWELVE-MONTH REVIEW.

Authors:  Tomaž Gračner
Journal:  Acta Clin Croat       Date:  2020-09       Impact factor: 0.780

  10 in total

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