Literature DB >> 24387491

Seeing the invisible: direct visualization of therapeutic radiation beams using air scintillation.

Benjamin Fahimian1, Andrew Ceballos2, Silvan Türkcan1, Daniel S Kapp1, Guillem Pratx1.   

Abstract

PURPOSE: To assess whether air scintillation produced during standard radiation treatments can be visualized and used to monitor a beam in a nonperturbing manner.
METHODS: Air scintillation is caused by the excitation of nitrogen gas by ionizing radiation. This weak emission occurs predominantly in the 300-430 nm range. An electron-multiplication charge-coupled device camera, outfitted with an f/0.95 lens, was used to capture air scintillation produced by kilovoltage photon beams and megavoltage electron beams used in radiation therapy. The treatment rooms were prepared to block background light and a short-pass filter was utilized to block light above 440 nm.
RESULTS: Air scintillation from an orthovoltage unit (50 kVp, 30 mA) was visualized with a relatively short exposure time (10 s) and showed an inverse falloff (r(2) = 0.89). Electron beams were also imaged. For a fixed exposure time (100 s), air scintillation was proportional to dose rate (r(2) = 0.9998). As energy increased, the divergence of the electron beam decreased and the penumbra improved. By irradiating a transparent phantom, the authors also showed that Cherenkov luminescence did not interfere with the detection of air scintillation. In a final illustration of the capabilities of this new technique, the authors visualized air scintillation produced during a total skin irradiation treatment.
CONCLUSIONS: Air scintillation can be measured to monitor a radiation beam in an inexpensive and nonperturbing manner. This physical phenomenon could be useful for dosimetry of therapeutic radiation beams or for online detection of gross errors during fractionated treatments.

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Year:  2014        PMID: 24387491     DOI: 10.1118/1.4851595

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  5 in total

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Review 2.  Radioluminescence in biomedicine: physics, applications, and models.

Authors:  Justin S Klein; Conroy Sun; Guillem Pratx
Journal:  Phys Med Biol       Date:  2019-02-06       Impact factor: 3.609

3.  Background luminescence in x-ray luminescence computed tomography (XLCT) imaging.

Authors:  Michael C Lun; Changqing Li
Journal:  Appl Opt       Date:  2019-02-01       Impact factor: 1.980

4.  Camera selection for real-time in vivo radiation treatment verification systems using Cherenkov imaging.

Authors:  Jacqueline M Andreozzi; Rongxiao Zhang; Adam K Glaser; Lesley A Jarvis; Brian W Pogue; David J Gladstone
Journal:  Med Phys       Date:  2015-02       Impact factor: 4.071

5.  Optical imaging method to quantify spatial dose variation due to the electron return effect in an MR-linac.

Authors:  Jacqueline M Andreozzi; Petr Brůža; Jochen Cammin; Brian W Pogue; David J Gladstone; Olga Green
Journal:  Med Phys       Date:  2019-12-25       Impact factor: 4.071

  5 in total

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