Literature DB >> 24382943

Design and Modeling of a 3-D Magnetic Actuator for Magnetic Microbead Manipulation.

Zhipeng Zhang1, Chia-Hsiang Menq2.   

Abstract

This paper presents the design, implementation, modeling, and analyses of a hexapole magnetic actuator that is capable of 3-D manipulation of a magnetic microbead. The magnetic actuator employs six sharp-tipped magnetic poles placed in hexapole configuration, six actuating coils, and a magnetic yoke. The magnetic poles concentrate the magnetic flux generated by the coils to the workspace, resulting in a high magnetic field with a large field gradient for magnetic force generation on the magnetic microbead. A lumped-parameter magnetic force model is then established to characterize nonlinearity of the magnetic force exerting on the magnetic microbead with respect to the applied currents to the coils and the position dependence of the magnetic force in the workspace. The force generation capability of the designed system is then explored using the force model. Moreover, an inverse force model is derived and its effect on the magnetic actuation capability is investigated. The inverse force model facilitates the implementation of a feedback control law to stabilize and control the motion of a magnetic microbead. Experimental results in terms of the magnetic force in relation to stable motion control of a magnetic microbead are used to validate the force model.

Entities:  

Keywords:  3-D magnetic actuation; Magnetic circuit; magnetic force model; magnetic micromanipulation

Year:  2011        PMID: 24382943      PMCID: PMC3875236          DOI: 10.1109/TMECH.2011.2105500

Source DB:  PubMed          Journal:  IEEE ASME Trans Mechatron        ISSN: 1083-4435            Impact factor:   5.303


  12 in total

1.  Analysis of cell mechanics in single vinculin-deficient cells using a magnetic tweezer.

Authors:  F J Alenghat; B Fabry; K Y Tsai; W H Goldmann; D E Ingber
Journal:  Biochem Biophys Res Commun       Date:  2000-10-14       Impact factor: 3.575

2.  Three-dimensional cellular deformation analysis with a two-photon magnetic manipulator workstation.

Authors:  Hayden Huang; Chen Y Dong; Hyuk-Sang Kwon; Jason D Sutin; Roger D Kamm; Peter T C So
Journal:  Biophys J       Date:  2002-04       Impact factor: 4.033

3.  Magnetic tweezers: micromanipulation and force measurement at the molecular level.

Authors:  Charlie Gosse; Vincent Croquette
Journal:  Biophys J       Date:  2002-06       Impact factor: 4.033

Review 4.  Magnetic tweezers: a sensitive tool to study DNA and chromatin at the single-molecule level.

Authors:  Jordanka Zlatanova; Sanford H Leuba
Journal:  Biochem Cell Biol       Date:  2003-06       Impact factor: 3.626

5.  Micro magnetic tweezers for nanomanipulation inside live cells.

Authors:  Anthony H B de Vries; Bea E Krenn; Roel van Driel; Johannes S Kanger
Journal:  Biophys J       Date:  2004-11-19       Impact factor: 4.033

6.  Thin-foil magnetic force system for high-numerical-aperture microscopy.

Authors:  J K Fisher; J Cribb; K V Desai; L Vicci; B Wilde; K Keller; R M Taylor; J Haase; K Bloom; E Timothy O'Brien; R Superfine
Journal:  Rev Sci Instrum       Date:  2006-02       Impact factor: 1.523

7.  High-force magnetic tweezers with force feedback for biological applications.

Authors:  Philip Kollmannsberger; Ben Fabry
Journal:  Rev Sci Instrum       Date:  2007-11       Impact factor: 1.523

8.  Best linear unbiased axial localization in three-dimensional fluorescent bead tracking with subnanometer resolution using off-focus images.

Authors:  Zhipeng Zhang; Chia-Hsiang Menq
Journal:  J Opt Soc Am A Opt Image Sci Vis       Date:  2009-06       Impact factor: 2.129

9.  Local measurements of viscoelastic parameters of adherent cell surfaces by magnetic bead microrheometry.

Authors:  A R Bausch; F Ziemann; A A Boulbitch; K Jacobson; E Sackmann
Journal:  Biophys J       Date:  1998-10       Impact factor: 4.033

10.  Measurement of local viscoelasticity and forces in living cells by magnetic tweezers.

Authors:  A R Bausch; W Möller; E Sackmann
Journal:  Biophys J       Date:  1999-01       Impact factor: 4.033

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  1 in total

1.  Design and Optimization of a New Alternating Electromagnetic-Field-Generation System for an Inverted Microscope.

Authors:  Zehao Wu; Ziheng Xu; Qingsong Xu
Journal:  Micromachines (Basel)       Date:  2022-03-30       Impact factor: 3.523

  1 in total

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