Literature DB >> 24382478

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases.

Li Gan1, Jeffrey A Johnson2.   

Abstract

Oxidative damage contributes to pathogenesis in many neurodegenerative diseases. As the indicator and regulator of oxidative stress, the Nrf2-ARE pathway has been shown dynamic changes and examined for its neuroprotective role in many cases. In this review, we summarize the progress of the Nrf2-ARE pathway in combating toxicity induced from typical misfolded protein aggregates in neurodegenerative diseases, and specifically the effects on the clearance of protein aggregates.
Copyright © 2013. Published by Elsevier B.V.

Entities:  

Keywords:  Misfolded proteins; Neurodegenerative diseases; Nrf2-ARE pathway; Oxidative stress

Mesh：

Substances：

Year:  2013        PMID： 24382478     DOI： 10.1016/j.bbadis.2013.12.011

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  71 in total

Review 1.  Disturbance of redox homeostasis as a contributing underlying pathomechanism of brain and liver alterations in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency.

Authors:  Guilhian Leipnitz; Carmen Regla Vargas; Moacir Wajner
Journal:  J Inherit Metab Dis       Date:  2015-06-04       Impact factor: 4.982

Review 2.  Oxidative stress response and Nrf2 signaling in aging.

Authors:  Hongqiao Zhang; Kelvin J A Davies; Henry Jay Forman
Journal:  Free Radic Biol Med       Date:  2015-06-09       Impact factor: 7.376

3.  Quercetin inhibits gout arthritis in mice: induction of an opioid-dependent regulation of inflammasome.

Authors:  Kenji W Ruiz-Miyazawa; Larissa Staurengo-Ferrari; Sandra S Mizokami; Talita P Domiciano; Fabiana T M C Vicentini; Doumit Camilios-Neto; Wander R Pavanelli; Phileno Pinge-Filho; Flávio A Amaral; Mauro M Teixeira; Rubia Casagrande; Waldiceu A Verri
Journal:  Inflammopharmacology       Date:  2017-05-15       Impact factor: 4.473

Review 4.  Type A and B monoamine oxidases distinctly modulate signal transduction pathway and gene expression to regulate brain function and survival of neurons.

Authors:  Makoto Naoi; Wakako Maruyama; Masayo Shamoto-Nagai
Journal:  J Neural Transm (Vienna)       Date:  2017-12-26       Impact factor: 3.575

5.  HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo.

Authors:  Dagmar E Ehrnhoefer; Amber L Southwell; Meenalochani Sivasubramanian; Xiaofan Qiu; Erika B Villanueva; Yuanyun Xie; Sabine Waltl; Lisa Anderson; Anita Fazeli; Lorenzo Casal; Boguslaw Felczak; Michelle Tsang; Michael R Hayden
Journal:  Hum Mol Genet       Date:  2018-01-15       Impact factor: 6.150

6.  Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.

Authors:  Wenqi Gao; Wei Wang; Jing Zhang; Pengyi Deng; Jun Hu; Jian Yang; Zhifang Deng
Journal:  Metab Brain Dis       Date:  2019-06-14       Impact factor: 3.584

7.  Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion.

Authors:  Zhenhua Xu; Hongkwan Cho; Matthew J Hartsock; Katherine L Mitchell; Junsong Gong; Lijuan Wu; Yanhong Wei; Shuang Wang; Rajesh K Thimmulappa; Michael B Sporn; Shyam Biswal; Derek S Welsbie; Elia J Duh
Journal:  J Neurochem       Date:  2015-03-04       Impact factor: 5.372

8.  Protective Role of tert-Butylhydroquinone Against Sodium Fluoride-Induced Oxidative Stress and Apoptosis in PC12 Cells.

Authors:  Jie Wu; Ming Cheng; Qiufang Liu; Jinghua Yang; Shengwen Wu; Xiaobo Lu; Cuihong Jin; Honglin Ma; Yuan Cai
Journal:  Cell Mol Neurobiol       Date:  2015-04-25       Impact factor: 5.046

9.  Intracerebral Glycine Administration Impairs Energy and Redox Homeostasis and Induces Glial Reactivity in Cerebral Cortex of Newborn Rats.

Authors:  Alana Pimentel Moura; Belisa Parmeggiani; Mateus Grings; Leonardo de Moura Alvorcem; Rafael Mello Boldrini; Anna Paula Bumbel; Marcela Moreira Motta; Bianca Seminotti; Moacir Wajner; Guilhian Leipnitz
Journal:  Mol Neurobiol       Date:  2015-10-26       Impact factor: 5.590

10.  Withania somnifera and Its Withanolides Attenuate Oxidative and Inflammatory Responses and Up-Regulate Antioxidant Responses in BV-2 Microglial Cells.

Authors:  Grace Y Sun; Runting Li; Jiankun Cui; Mark Hannink; Zezong Gu; Kevin L Fritsche; Dennis B Lubahn; Agnes Simonyi
Journal:  Neuromolecular Med       Date:  2016-05-21       Impact factor: 3.843
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.