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Literature DB >> 24381646

The role of obesity in gastrointestinal cancer: evidence and opinion.

Claire L Donohoe¹, Naoimh J O'Farrell¹, Suzanne L Doyle¹, John V Reynolds².

Abstract

There is increasing recognition of the impact of being overweight and obese on the development of cancers at diverse sites including the gastrointestinal tract. Large epidemiological studies indicate that up to 14% of tumours may be related to obesity. Pathophysiological mechanisms underpinning this association are not well understood and so are discussed in this review.

Entities: Disease

Keywords: adipose tissue, carcinogenesis; inflammation; signalling pathways; visceral adiposity

Year: 2014 PMID： 24381646 PMCID： PMC3871278 DOI： 10.1177/1756283X13501786

Source DB: PubMed Journal: Therap Adv Gastroenterol ISSN： 1756-283X Impact factor: 4.409

126 in total

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14 in total

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Authors: Elizabeth Long; Ian L P Beales
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Review 4. Gastroesophageal Cancer After Gastric Bypass Surgeries: a Systematic Review and Meta-analysis.

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