Literature DB >> 24378783

Opening the lead generation toolbox.

Peter B Simpson1, Melvin Reichman2.   

Abstract

Mesh：

Year:  2014        PMID： 24378783     DOI： 10.1038/nrd4202

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  4 in total

Review 1.  How to improve R&D productivity: the pharmaceutical industry's grand challenge.

Authors:  Steven M Paul; Daniel S Mytelka; Christopher T Dunwiddie; Charles C Persinger; Bernard H Munos; Stacy R Lindborg; Aaron L Schacht
Journal:  Nat Rev Drug Discov       Date:  2010-02-19       Impact factor: 84.694

Review 2.  Overcoming the challenges of drug discovery for neglected tropical diseases: the A·WOL experience.

Authors:  Kelly L Johnston; Louise Ford; Mark J Taylor
Journal:  J Biomol Screen       Date:  2013-11-15

Review 3.  Big pharma screening collections: more of the same or unique libraries? The AstraZeneca-Bayer Pharma AG case.

Authors:  Thierry Kogej; Niklas Blomberg; Peter J Greasley; Stefan Mundt; Mikko J Vainio; Jens Schamberger; Georg Schmidt; Jörg Hüser
Journal:  Drug Discov Today       Date:  2012-11-03       Impact factor: 7.851

4.  European lead factory opens for business.

Authors:  Asher Mullard
Journal:  Nat Rev Drug Discov       Date:  2013-03       Impact factor: 84.694
  4 in total
  5 in total

1.  Towards a hit for every target.

Authors:  Steve Rees; Philip Gribbon; Karen Birmingham; William P Janzen; Garry Pairaudeau
Journal:  Nat Rev Drug Discov       Date:  2015-11-20       Impact factor: 84.694

2.  The toolbox is open, but who should pay for the job?

Authors:  John E Ladbury; Adrian Hall; John Skidmore
Journal:  Nat Rev Drug Discov       Date:  2014-07       Impact factor: 84.694

Review 3.  Current Drug Repurposing Strategies for Rare Neurodegenerative Disorders.

Authors:  Sweta Shah; Marc Marie Dooms; Sofia Amaral-Garcia; Mariana Igoillo-Esteve
Journal:  Front Pharmacol       Date:  2021-12-21       Impact factor: 5.810

Review 4.  Drug repurposing for antimicrobial discovery.

Authors:  Maya A Farha; Eric D Brown
Journal:  Nat Microbiol       Date:  2019-03-04       Impact factor: 17.745

5.  A High-Throughput Cellular Screening Assay for Small-Molecule Inhibitors and Activators of Cytoplasmic Dynein-1-Based Cargo Transport.

Authors:  John Vincent; Marian Preston; Elizabeth Mouchet; Nicolas Laugier; Adam Corrigan; Jérôme Boulanger; Dean G Brown; Roger Clark; Mark Wigglesworth; Andrew P Carter; Simon L Bullock
Journal:  SLAS Discov       Date:  2020-05-21       Impact factor: 3.341
  5 in total

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