BACKGROUND: Low-dose rate brachytherapy is a well established treatment modality of oral cancer. Data about high-dose rate (HDR) brachytherapy are still sparse with various fractionation schedules and heterogeneous results. AIM: The aim of our retrospective study was to evaluate the results of HDR brachytherapy with doses of 3 Gy twice daily. PATIENTS AND METHODS: Twenty patients with squamous cell tongue cancer were treated in the years 2001-2009 by exclusive HDR BT 18 × 3 Gy twice daily. The plastic tube technique was used. Median follow up was 47 months (7.8-118) since brachytherapy. RESULTS: The local and locoregional control was 85% and 68%, respectively. Bone necrosis developed in one case treated without mandibular shielding and soft tissue necrosis in 2 cases. CONCLUSION: It can be concluded that HDR brachytherapy with 18 × 3 Gy twice daily is safe with promising local control. The risk of nodal recurrences is substantial.
BACKGROUND: Low-dose rate brachytherapy is a well established treatment modality of oral cancer. Data about high-dose rate (HDR) brachytherapy are still sparse with various fractionation schedules and heterogeneous results. AIM: The aim of our retrospective study was to evaluate the results of HDR brachytherapy with doses of 3 Gy twice daily. PATIENTS AND METHODS: Twenty patients with squamous cell tongue cancer were treated in the years 2001-2009 by exclusive HDR BT 18 × 3 Gy twice daily. The plastic tube technique was used. Median follow up was 47 months (7.8-118) since brachytherapy. RESULTS: The local and locoregional control was 85% and 68%, respectively. Bone necrosis developed in one case treated without mandibular shielding and soft tissue necrosis in 2 cases. CONCLUSION: It can be concluded that HDR brachytherapy with 18 × 3 Gy twice daily is safe with promising local control. The risk of nodal recurrences is substantial.
Entities:
Keywords:
High-dose rate brachytherapy; Oral cancer
Authors: J J Mazeron; J M Crook; V Benck; G Marinello; M Martin; M Raynal; E Haddad; R Peynègre; J P Le Bourgeois; W Walop Journal: Int J Radiat Oncol Biol Phys Date: 1990-12 Impact factor: 7.038
Authors: Jose Luis Guinot; Miguel Santos; Maria Isabel Tortajada; Maria Carrascosa; Enrique Estellés; Juan Bosco Vendrell; Rodrigo Muelas; Maria Luisa Chust; Jose Luis Mengual; Leoncio Arribas Journal: Brachytherapy Date: 2010-01-29 Impact factor: 2.362
Authors: V Benk; J J Mazeron; L Grimard; J Crook; E Haddad; P Piedbois; E Calitchi; M Raynal; M Martin; J P Le Bourgeois Journal: Radiother Oncol Date: 1990-08 Impact factor: 6.280