OBJECTIVE: This retrospective clinical study evaluated the usefulness of high-dose rate (HDR) brachytherapy for stage I-II tongue cancer in comparison with traditional low-dose rate (LDR) brachytherapy. MATERIALS AND METHODS: Twenty-five patients with stage I-II tongue cancer underwent HDR between 1995 and 1999. The status of local control and late neck metastasis, survival rate, and frequency of osteonecrosis in these patients were examined in comparison with a historical control made up of 71 patients who underwent LDR between 1980 and 1995. RESULTS: The local control rate and survival rate were lower in the HDR group than in the LDR group. There were no apparent differences in the frequency of late neck metastasis between the two groups. Osteonecrosis occurred earlier and more frequently in the HDR group. CONCLUSION: We would caution the use of HDR brachytherapy until further studies are done in many institutions.
OBJECTIVE: This retrospective clinical study evaluated the usefulness of high-dose rate (HDR) brachytherapy for stage I-II tongue cancer in comparison with traditional low-dose rate (LDR) brachytherapy. MATERIALS AND METHODS: Twenty-five patients with stage I-II tongue cancer underwent HDR between 1995 and 1999. The status of local control and late neck metastasis, survival rate, and frequency of osteonecrosis in these patients were examined in comparison with a historical control made up of 71 patients who underwent LDR between 1980 and 1995. RESULTS: The local control rate and survival rate were lower in the HDR group than in the LDR group. There were no apparent differences in the frequency of late neck metastasis between the two groups. Osteonecrosis occurred earlier and more frequently in the HDR group. CONCLUSION: We would caution the use of HDR brachytherapy until further studies are done in many institutions.
Authors: Douglas E Peterson; Wolfgang Doerr; Allan Hovan; Andres Pinto; Debbie Saunders; Linda S Elting; Fred K L Spijkervet; Michael T Brennan Journal: Support Care Cancer Date: 2010-06-06 Impact factor: 3.603
Authors: Lubos Tuček; Jiri Petera; Igor Sirák; Milan Vošmik; Helena Doležalová; Simona Brokešová; Miroslav Hodek; Linda Kašaová; Petr Paluska Journal: Rep Pract Oncol Radiother Date: 2011-08-06
Authors: Sung Uk Lee; Kwan Ho Cho; Sung Ho Moon; Sung Weon Choi; Joo Yong Park; Tak Yun; Sang Hyun Lee; Young Kyung Lim; Chi Young Jeong Journal: Radiat Oncol J Date: 2014-12-30