Arisa E Ortiz1, Mathew M Avram, Molly A Wanner. 1. Dermatology Cosmetic and Laser Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, 02114; Wellman Center for Photomedicine, Boston, Massachusetts, 02114; UC San Diego, San Diego, California, 92122.
Abstract
BACKGROUND AND OBJECTIVE: Onychomycosis is a common fungal infection that affects many individuals. Systemic therapies are effective, but are limited by their side effects and potential for hepatotoxicity. Topical therapies have less serious side effects, yet provide only limited efficacy due to their inability to penetrate the nail plate. These limitations have led to the investigation of laser and light-based modalities as alternative treatment options for onychomycosis. This article will provide an overview and critical assessment of the field of laser and other energy-based treatments for onychomycosis. STUDY DESIGN/ MATERIALS AND METHODS: A literature search was conducted on laser and light-based treatments for onychomycosis. RESULTS: Early data are promising, however, many of these studies are small or poorly designed. CONCLUSION: Further evaluation and larger studies are needed to determine the optimal light source, pulse duration, and treatment schedule for long-term success.
BACKGROUND AND OBJECTIVE:Onychomycosis is a common fungal infection that affects many individuals. Systemic therapies are effective, but are limited by their side effects and potential for hepatotoxicity. Topical therapies have less serious side effects, yet provide only limited efficacy due to their inability to penetrate the nail plate. These limitations have led to the investigation of laser and light-based modalities as alternative treatment options for onychomycosis. This article will provide an overview and critical assessment of the field of laser and other energy-based treatments for onychomycosis. STUDY DESIGN/ MATERIALS AND METHODS: A literature search was conducted on laser and light-based treatments for onychomycosis. RESULTS: Early data are promising, however, many of these studies are small or poorly designed. CONCLUSION: Further evaluation and larger studies are needed to determine the optimal light source, pulse duration, and treatment schedule for long-term success.
Authors: Antonio Zalacain; Alejandra Merlos; Elena Planell; Erica G Cantadori; Teresa Vinuesa; Miguel Viñas Journal: Lasers Med Sci Date: 2017-04-04 Impact factor: 3.161