Literature DB >> 24371073

Murine gammaherpesvirus 68 encodes a second PML-modifying protein.

Jaturong Sewatanon1, Paul D Ling.   

Abstract

The ORF75c tegument protein of murine gammaherpesvirus 68 (MHV68) promotes the degradation of the antiviral promyelocytic leukemia (PML) protein. Surprisingly, MHV68 expressing a degradation-deficient ORF75c replicated in cell culture and in mice similar to the wild-type virus. However, in cells infected with this mutant virus, PML formed novel track-like structures that are induced by ORF61, the viral ribonucleotide reductase large subunit. These findings may explain why ORF75c mutant viruses unable to degrade PML had no demonstrable phenotype after infection.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 24371073      PMCID： PMC3957941          DOI： 10.1128/JVI.03081-13

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  35 in total

1.  Gammaherpesvirus lytic gene expression as characterized by DNA array.

Authors:  Joo Wook Ahn; Kenneth L Powell; Paul Kellam; Dagmar G Alber
Journal:  J Virol       Date:  2002-06       Impact factor: 5.103

2.  The R1 subunit of herpes simplex virus ribonucleotide reductase protects cells against apoptosis at, or upstream of, caspase-8 activation.

Authors:  Yves Langelier; Stéphane Bergeron; Stéphane Chabaud; Julie Lippens; Claire Guilbault; A Marie-Josée Sasseville; Stéphan Denis; Dick D Mosser; Bernard Massie
Journal:  J Gen Virol       Date:  2002-11       Impact factor: 3.891

3.  Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein.

Authors:  Claudia Mack; Albert Sickmann; David Lembo; Wolfram Brune
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-19       Impact factor: 11.205

4.  The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms.

Authors:  R D Everett; P Freemont; H Saitoh; M Dasso; A Orr; M Kathoria; J Parkinson
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

5.  Epstein-barr virus immediate-early protein BZLF1 is SUMO-1 modified and disrupts promyelocytic leukemia bodies.

Authors:  A L Adamson; S Kenney
Journal:  J Virol       Date:  2001-03       Impact factor: 5.103

6.  Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

Authors:  V Doucas; A M Ishov; A Romo; H Juguilon; M D Weitzman; R M Evans; G G Maul
Journal:  Genes Dev       Date:  1996-01-15       Impact factor: 11.361

7.  PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0.

Authors:  Chris Boutell; Anne Orr; Roger D Everett
Journal:  J Virol       Date:  2003-08       Impact factor: 5.103

8.  Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1.

Authors:  Jason W Upton; William J Kaiser; Edward S Mocarski
Journal:  J Biol Chem       Date:  2008-04-28       Impact factor: 5.157

9.  Murine gammaherpesvirus 68 open reading frame 75c tegument protein induces the degradation of PML and is essential for production of infectious virus.

Authors:  Paul D Ling; Jie Tan; Jaturong Sewatanon; RongSheng Peng
Journal:  J Virol       Date:  2008-05-28       Impact factor: 5.103

10.  Multiple functions for ORF75c in murid herpesvirus-4 infection.

Authors:  Miguel Gaspar; Michael B Gill; Jens-Bernhard Lösing; Janet S May; Philip G Stevenson
Journal:  PLoS One       Date:  2008-07-23       Impact factor: 3.240
View more
  4 in total

1.  Viral FGARAT Homolog ORF75 of Rhesus Monkey Rhadinovirus Effects Proteasomal Degradation of the ND10 Components SP100 and PML.

Authors:  Alexander S Hahn; Anna K Großkopf; Doris Jungnickl; Brigitte Scholz; Armin Ensser
Journal:  J Virol       Date:  2016-08-12       Impact factor: 5.103

Review 2.  Disruption of host antiviral resistances by gammaherpesvirus tegument proteins with homology to the FGARAT purine biosynthesis enzyme.

Authors:  Kevin Tsai; Troy E Messick; Paul M Lieberman
Journal:  Curr Opin Virol       Date:  2015-08-07       Impact factor: 7.090

Review 3.  Gammaherpesviral Tegument Proteins, PML-Nuclear Bodies and the Ubiquitin-Proteasome System.

Authors:  Florian Full; Alexander S Hahn; Anna K Großkopf; Armin Ensser
Journal:  Viruses       Date:  2017-10-21       Impact factor: 5.048

4.  Viral FGARAT ORF75A promotes early events in lytic infection and gammaherpesvirus pathogenesis in mice.

Authors:  Nick D Van Skike; Nana K Minkah; Chad H Hogan; Gary Wu; Peter T Benziger; Darby G Oldenburg; Mehmet Kara; Deborah M Kim-Holzapfel; Douglas W White; Scott A Tibbetts; Jarrod B French; Laurie T Krug
Journal:  PLoS Pathog       Date:  2018-02-01       Impact factor: 6.823
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.