Literature DB >> 24370739

A developmental program drives aggressive embryonal brain tumors.

Tenley C Archer1, Scott L Pomeroy1.   

Abstract

Embryonal tumors with multilayered rosettes (ETMRs) are primitive neuroectodermal tumors arising in infants. A new study shows that these tumors are universally driven by fusion of the promoter of a gene with brain-specific expression, TTYH1, to C19MC, the largest human microRNA cluster, activating a fetal neural development program.

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Year:  2014        PMID： 24370739     DOI： 10.1038/ng.2857

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  15 in total

Review 1.  Molecular diagnostics in embryonal brain tumors.

Authors:  Charles G Eberhart
Journal:  Brain Pathol       Date:  2011-01       Impact factor: 6.508

2.  Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.

Authors:  Claudia L Kleinman; Noha Gerges; Simon Papillon-Cavanagh; Patrick Sin-Chan; Albena Pramatarova; Dong-Anh Khuong Quang; Véronique Adoue; Stephan Busche; Maxime Caron; Haig Djambazian; Amandine Bemmo; Adam M Fontebasso; Tara Spence; Jeremy Schwartzentruber; Steffen Albrecht; Peter Hauser; Miklos Garami; Almos Klekner; Laszlo Bognar; Jose-Luis Montes; Alfredo Staffa; Alexandre Montpetit; Pierre Berube; Magdalena Zakrzewska; Krzysztof Zakrzewski; Pawel P Liberski; Zhifeng Dong; Peter M Siegel; Thomas Duchaine; Christian Perotti; Adam Fleming; Damien Faury; Marc Remke; Marco Gallo; Peter Dirks; Michael D Taylor; Robert Sladek; Tomi Pastinen; Jennifer A Chan; Annie Huang; Jacek Majewski; Nada Jabado
Journal:  Nat Genet       Date:  2013-12-08       Impact factor: 38.330

3.  Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis.

Authors:  Jian-Jun Zhao; Juhua Yang; Jianhong Lin; Nan Yao; Yihua Zhu; Jianlong Zheng; Jianhua Xu; Jin Q Cheng; Jian-Yin Lin; Xu Ma
Journal:  Childs Nerv Syst       Date:  2008-09-26       Impact factor: 1.475

4.  Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors.

Authors:  Meihua Li; Kyle F Lee; Yuntao Lu; Ian Clarke; David Shih; Charles Eberhart; V Peter Collins; Tim Van Meter; Daniel Picard; Limei Zhou; Paul C Boutros; Piergiorgio Modena; Muh-Lii Liang; Steve W Scherer; Eric Bouffet; James T Rutka; Scott L Pomeroy; Ching C Lau; Michael D Taylor; Amar Gajjar; Peter B Dirks; Cynthia E Hawkins; Annie Huang
Journal:  Cancer Cell       Date:  2009-12-08       Impact factor: 31.743

5.  The two stem cell microRNA gene clusters C19MC and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomas.

Authors:  Volkhard Rippe; Lea Dittberner; Verena N Lorenz; Norbert Drieschner; Rolf Nimzyk; Wolfgang Sendt; Klaus Junker; Gazanfer Belge; Jörn Bullerdiek
Journal:  PLoS One       Date:  2010-03-03       Impact factor: 3.240

6.  The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis.

Authors:  Qihong Huang; Kiranmai Gumireddy; Mariette Schrier; Carlos le Sage; Remco Nagel; Suresh Nair; David A Egan; Anping Li; Guanghua Huang; Andres J Klein-Szanto; Phyllis A Gimotty; Dionyssios Katsaros; George Coukos; Lin Zhang; Ellen Puré; Reuven Agami
Journal:  Nat Cell Biol       Date:  2008-01-13       Impact factor: 28.824

7.  Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis.

Authors:  Daniel Picard; Suzanne Miller; Cynthia E Hawkins; Eric Bouffet; Hazel A Rogers; Tiffany S Y Chan; Seung-Ki Kim; Young-Shin Ra; Jason Fangusaro; Andrey Korshunov; Helen Toledano; Hideo Nakamura; James T Hayden; Jennifer Chan; Lucie Lafay-Cousin; Pingzhao Hu; Xing Fan; Karin M Muraszko; Scott L Pomeroy; Ching C Lau; Ho-Keung Ng; Chris Jones; Timothy Van Meter; Steven C Clifford; Charles Eberhart; Amar Gajjar; Stefan M Pfister; Richard G Grundy; Annie Huang
Journal:  Lancet Oncol       Date:  2012-06-11       Impact factor: 41.316

8.  An Oct4-Sall4-Nanog network controls developmental progression in the pre-implantation mouse embryo.

Authors:  Meng How Tan; Kin Fai Au; Denise E Leong; Kira Foygel; Wing H Wong; Mylene Wm Yao
Journal:  Mol Syst Biol       Date:  2013       Impact factor: 11.429

9.  DNA methyltransferase 3B expression is associated with poor outcome of stage I testicular seminoma.

Authors:  Eri Arai; Tohru Nakagawa; Saori Wakai-Ushijima; Hiroyuki Fujimoto; Yae Kanai
Journal:  Histopathology       Date:  2012-03-06       Impact factor: 5.087

10.  High DNA methyltransferase DNMT3B levels: a poor prognostic marker in acute myeloid leukemia.

Authors:  Sandrine Hayette; Xavier Thomas; Laurent Jallades; Kaddour Chabane; Carole Charlot; Isabelle Tigaud; Sophie Gazzo; Stéphane Morisset; Pascale Cornillet-Lefebvre; Adriana Plesa; Sarah Huet; Aline Renneville; Gilles Salles; Franck Emmanuel Nicolini; Jean-Pierre Magaud; Mauricette Michallet
Journal:  PLoS One       Date:  2012-12-10       Impact factor: 3.240
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  5 in total

1.  NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma.

Authors:  Alex Panaccione; Michael T Chang; Beatrice E Carbone; Yan Guo; Christopher A Moskaluk; Renu K Virk; Luis Chiriboga; Manju L Prasad; Benjamin Judson; Saral Mehra; Wendell G Yarbrough; Sergey V Ivanov
Journal:  Clin Cancer Res       Date:  2016-04-15       Impact factor: 12.531

Review 2.  MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknown.

Authors:  Maria Braoudaki; George I Lambrou
Journal:  J Hematol Oncol       Date:  2015-02-06       Impact factor: 17.388

Review 3.  The microRNA-183 cluster: the family that plays together stays together.

Authors:  Shweta Dambal; Mit Shah; Brittany Mihelich; Larisa Nonn
Journal:  Nucleic Acids Res       Date:  2015-07-13       Impact factor: 16.971

Review 4.  The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25.

Authors:  Cuong Khuu; Tor Paaske Utheim; Amer Sehic
Journal:  Scientifica (Cairo)       Date:  2016-04-04

5.  The tweety Gene Family: From Embryo to Disease.

Authors:  Rithvik R Nalamalapu; Michelle Yue; Aaron R Stone; Samantha Murphy; Margaret S Saha
Journal:  Front Mol Neurosci       Date:  2021-06-28       Impact factor: 5.639
  5 in total

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