Literature DB >> 24366616

The role of radiotherapy in the management of sinonasal melanoma and its impact on patients and healthcare professionals.

A Moore1.   

Abstract

The aim of this paper is discuss the contemporary issues surrounding radiotherapy for sinonasal mucosal melanoma (SNMM). SNMM is a rare disease with a poor prognosis. The particular challenge with regard to radiotherapy for SNMM is that melanoma is a relatively radioresistant tumour in an anatomical site surrounded by important radiosensitive structures. IMRT has been shown to be an effective primary and adjuvant therapy, and is superior to traditional photon radiotherapy techniques. Emerging evidence also supports the role of particle therapy. Protons and carbon ions may provide a superior target dose and less collateral damage than IMRT. Stereotactic radiotherapy has also been used successfully. The introduction of new technology will always be inhibited by financial constraints and concerns about long-term efficacy. The role of the health professional will change commensurate with the introduction of new technology in terms of the knowledge and the clinical skills they must acquire. Working patterns may need to change to manage the competing interests of expanding services and financial cutbacks. In addition to the clinical expertise health professionals provide, they will be charged with the responsibility of finding innovative ways to improve and develop radiotherapy services for SNMM.

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Year:  2013        PMID: 24366616     DOI: 10.1007/s00405-013-2868-3

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  31 in total

1.  Referring patients abroad for proton therapy.

Authors:  E Wilson
Journal:  Clin Oncol (R Coll Radiol)       Date:  2000       Impact factor: 4.126

2.  Outcomes of visual acuity in carbon ion radiotherapy: analysis of dose-volume histograms and prognostic factors.

Authors:  Azusa Hasegawa; Jun-etsu Mizoe; Atsushi Mizota; Hirohiko Tsujii
Journal:  Int J Radiat Oncol Biol Phys       Date:  2005-09-22       Impact factor: 7.038

3.  Outcome of sinonasal melanoma: clinical experience and review of the literature.

Authors:  Thomas N Roth; Carole Gengler; Gerhard F Huber; David Holzmann
Journal:  Head Neck       Date:  2010-10       Impact factor: 3.147

Review 4.  Management of mucosal melanomas of the head and neck: did we make any progress?

Authors:  Mauricio A Moreno; Ehab Y Hanna
Journal:  Curr Opin Otolaryngol Head Neck Surg       Date:  2010-04       Impact factor: 2.064

Review 5.  Review: mucosal melanoma of the head and neck.

Authors:  Haim Gavriel; Grant McArthur; Andrew Sizeland; Michael Henderson
Journal:  Melanoma Res       Date:  2011-08       Impact factor: 3.599

6.  Assessment of early toxicity and response in patients treated with proton and carbon ion therapy at the Heidelberg ion therapy center using the raster scanning technique.

Authors:  Stefan Rieken; Daniel Habermehl; Anna Nikoghosyan; Alexandra Jensen; Thomas Haberer; Oliver Jäkel; Marc W Münter; Thomas Welzel; Jürgen Debus; Stephanie E Combs
Journal:  Int J Radiat Oncol Biol Phys       Date:  2011-02-06       Impact factor: 7.038

7.  Proton beam therapy as a nonsurgical approach to mucosal melanoma of the head and neck: a pilot study.

Authors:  Sadamoto Zenda; Mitsuhiko Kawashima; Teiji Nishio; Ryosuke Kohno; Keiji Nihei; Masakatsu Onozawa; Satoko Arahira; Takashi Ogino
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-10-13       Impact factor: 7.038

Review 8.  Survey of the availability and use of advanced radiotherapy technology in the UK.

Authors:  W P M Mayles
Journal:  Clin Oncol (R Coll Radiol)       Date:  2010-07-27       Impact factor: 4.126

9.  Dose escalation study of carbon ion radiotherapy for locally advanced head-and-neck cancer.

Authors:  Jun-Etsu Mizoe; Hirohiko Tsujii; Tadashi Kamada; Yoshisuke Matsuoka; Hiroshi Tsuji; Yasuhiro Osaka; Azusa Hasegawa; Nobuharu Yamamoto; Satoshi Ebihara; Akiyoshi Konno
Journal:  Int J Radiat Oncol Biol Phys       Date:  2004-10-01       Impact factor: 7.038

10.  Inhibition of constitutively activated nuclear factor-kappaB radiosensitizes human melanoma cells.

Authors:  Anupama Munshi; John F Kurland; Takashi Nishikawa; Paul J Chiao; Michael Andreeff; Raymond E Meyn
Journal:  Mol Cancer Ther       Date:  2004-08       Impact factor: 6.261

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  1 in total

Review 1.  Mucosal Melanoma: a Literature Review.

Authors:  Simon Skovsted Yde; Pia Sjoegren; Martin Heje; Lars B Stolle
Journal:  Curr Oncol Rep       Date:  2018-03-23       Impact factor: 5.075

  1 in total

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