| Literature DB >> 2435649 |
M Leader, M Collins, J Patel, K Henry.
Abstract
In this study we examined 198 sarcomas, 38 carcinomas, 13 'tumours with a spindle cell component' and 22 malignant melanomas with a commercial monoclonal vimentin antibody. All histopathological material was formalin fixed and paraffin embedded. The results show this antibody to be a sensitive and specific marker of mesenchymal derivation or differentiation. It is a useful tool in separating sarcomas from most carcinomas, and in separating malignant melanomas from carcinomas. When used in combination with a cytokeratin antibody it identifies carcinosarcomas and synovial sarcomas.Entities:
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Year: 1987 PMID： 2435649 DOI： 10.1111/j.1365-2559.1987.tb02609.x
Source DB: PubMed Journal: Histopathology ISSN： 0309-0167 Impact factor: 5.087