| Literature DB >> 2435574 |
P Cantatore, Z Flagella, F Fracasso, A M Lezza, M N Gadaleta, A de Montalvo.
Abstract
The synthesis and turnover rates of the two 12 S and 16 S mt rRNAs and of the mt mRNAs for subunits I and III of cytochrome oxidase have been determined by measuring the kinetics of incorporation of [3H]uridine in the mtRNA of rat hepatocytes. All the RNA species examined have approximately the same turnover (t1/2 approximately 100 min) and therefore the rate of synthesis, which is about 10-times higher for the rRNAs, seems to be the factor responsible for the different mt rRNA and mRNA steady-state levels.Entities:
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Year: 1987 PMID: 2435574 DOI: 10.1016/0014-5793(87)81480-1
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124