Literature DB >> 2435574

Synthesis and turnover rates of four rat liver mitochondrial RNA species.

P Cantatore, Z Flagella, F Fracasso, A M Lezza, M N Gadaleta, A de Montalvo.   

Abstract

The synthesis and turnover rates of the two 12 S and 16 S mt rRNAs and of the mt mRNAs for subunits I and III of cytochrome oxidase have been determined by measuring the kinetics of incorporation of [3H]uridine in the mtRNA of rat hepatocytes. All the RNA species examined have approximately the same turnover (t1/2 approximately 100 min) and therefore the rate of synthesis, which is about 10-times higher for the rRNAs, seems to be the factor responsible for the different mt rRNA and mRNA steady-state levels.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 2435574     DOI: 10.1016/0014-5793(87)81480-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  13 in total

1.  Large functional range of steady-state levels of nuclear and mitochondrial transcripts coding for the subunits of the human mitochondrial OXPHOS system.

Authors:  Hervé Duborjal; Réjane Beugnot; Bénédicte Mousson de Camaret; Jean-Paul Issartel
Journal:  Genome Res       Date:  2002-12       Impact factor: 9.043

2.  Molecular characterization and cloning of sheep mitochondrial DNA.

Authors:  M Villalta; P Fernández-Silva; B Beltrán; L Enguita; M J López-Pérez; J Montoya
Journal:  Curr Genet       Date:  1992-03       Impact factor: 3.886

3.  Mitochondrial gene expression in small intestinal epithelial cells.

Authors:  T P Mayall; I Bjarnason; U Y Khoo; T J Peters; A J Macpherson
Journal:  Biochem J       Date:  1995-06-01       Impact factor: 3.857

4.  Transient activation of mitochondrial translation regulates the expression of the mitochondrial genome during mammalian mitochondrial differentiation.

Authors:  L K Ostronoff; J M Izquierdo; J A Enríquez; J Montoya; J M Cuezva
Journal:  Biochem J       Date:  1996-05-15       Impact factor: 3.857

5.  The Roles of Mutation, Selection, and Expression in Determining Relative Rates of Evolution in Mitochondrial versus Nuclear Genomes.

Authors:  Justin C Havird; Daniel B Sloan
Journal:  Mol Biol Evol       Date:  2016-08-25       Impact factor: 16.240

6.  Faithful and highly efficient RNA synthesis in isolated mitochondria from rat liver.

Authors:  P Cantatore; P Loguercio Polosa; A Mustich; V Petruzzella; M N Gadaleta
Journal:  Curr Genet       Date:  1988-11       Impact factor: 3.886

7.  ATP synthesis is coupled to rat liver mitochondrial RNA synthesis.

Authors:  S F DasGupta; S I Rapoport; M Gerschenson; E Murphy; G Fiskum; S J Russell; K Chandrasekaran
Journal:  Mol Cell Biochem       Date:  2001-05       Impact factor: 3.396

8.  Import of mitochondrial transcription factor A (TFAM) into rat liver mitochondria stimulates transcription of mitochondrial DNA.

Authors:  Heike L Garstka; Wolfgang E Schmitt; Jeanette Schultz; Bettina Sogl; Barbara Silakowski; Acisclo Pérez-Martos; Julio Montoya; Rudolf J Wiesner
Journal:  Nucleic Acids Res       Date:  2003-09-01       Impact factor: 16.971

9.  Effects on mitochondrial transcription of manipulating mTERF protein levels in cultured human HEK293 cells.

Authors:  Anne K Hyvärinen; Mona K Kumanto; Sanna K Marjavaara; Howard T Jacobs
Journal:  BMC Mol Biol       Date:  2010-09-16       Impact factor: 2.946

10.  MITOCHIP assessment of differential gene expression in the skeletal muscle of Ant1 knockout mice: coordinate regulation of OXPHOS, antioxidant, and apoptotic genes.

Authors:  Vaidya Subramaniam; Pawel Golik; Deborah G Murdock; Shawn Levy; Keith W Kerstann; Pinar E Coskun; Goarik A Melkonian; Douglas C Wallace
Journal:  Biochim Biophys Acta       Date:  2008-03-28
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.