| Literature DB >> 24355245 |
Aili Cui1, Zhen Zhu1, Meng Chen2, Huanying Zheng3, Leng Liu3, Yan Wang4, Yan Ma4, Changyin Wang5, Xueqiang Fang5, Ping Li6, Ronghui Guan6, Shuang Wang7, Jianhui Zhou7, Lei Zheng8, Hui Gao8, Zhengrong Ding9, Liqun Li9, Fang Bo10, Zhaodan Sun10, Zhenying Zhang11, Daxing Feng11, Jilan He12, Hui Chen13, Li Jin14, Paul A Rota15, Wenbo Xu16.
Abstract
The epidemiologic and genetic characteristics of mumps viruses detected in China from 1995 to 2010 were analyzed in this study. Mumps remains endemic in China with a high overall incidence rate. The incidence of mumps in Western China was higher than that in other regions of the country. Each year, most of mumps cases occurred between April and July, but a small peak also occurred in November and December. Mumps cases primarily affected the under 15 year old age group. Virologic data demonstrated that genotype F was the predominant circulating genotype throughout China for at least 15 years and no other genotype was detected between 1995 and 2010. Analysis of sequence data from the small hydrophobic (SH) gene indicated that multiple transmission chains of genotype F were found in various provinces of China, with no apparent chronologic and geographic restriction. This is the first report describing the epidemiology of mumps and genetic characterization of mumps viruses at the national level in China.Keywords: Epidemiology; Genetic characteristics; Mumps virus
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Year: 2013 PMID： 24355245 DOI： 10.1016/j.meegid.2013.12.005
Source DB: PubMed Journal: Infect Genet Evol ISSN： 1567-1348 Impact factor: 3.342