| Literature DB >> 24348868 |
Andrew J Giustini1, Alicia A Petryk2, Shiraz M Cassim2, Jennifer A Tate2, Ian Baker2, P Jack Hoopes3.
Abstract
The activation of magnetic nanoparticles (mNPs) by an alternating magnetic field (AMF) is currently being explored as technique for targeted therapeutic heating of tumors. Various types of superparamagnetic and ferromagnetic particles, with different coatings and targeting agents, allow for tumor site and type specificity. Magnetic nanoparticle hyperthermia is also being studied as an adjuvant to conventional chemotherapy and radiation therapy. This review provides an introduction to some of the relevant biology and materials science involved in the technical development and current and future use of mNP hyperthermia as clinical cancer therapy.Entities:
Keywords: Magnetic nanoparticle; cancer; hyperthermia; tumor
Year: 2010 PMID: 24348868 PMCID: PMC3859910 DOI: 10.1142/S1793984410000067
Source DB: PubMed Journal: Nano Life ISSN: 1793-9844