| Literature DB >> 2434863 |
J M Balloul, P Sondermeyer, D Dreyer, M Capron, J M Grzych, R J Pierce, D Carvallo, J P Lecocq, A Capron.
Abstract
The complementary DNA sequence encoding the Mr 28,000 antigen of Schistosoma mansoni has been isolated and expressed in Escherichia coli. Experimental vaccination of rats, hamsters and monkeys with a recombinant fusion protein induces a strongly cytotoxic antibody response. Immunization of rats and hamsters with this protein leads to significant protection against a natural challenge infection with live cercariae.Entities:
Mesh:
Substances:
Year: 1987 PMID: 2434863 DOI: 10.1038/326149a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962