Literature DB >> 24348118

Seizures, Cerebral Shutdown, and SUDEP.

Alireza Bozorgi1, Samden D Lhatoo1.   

Abstract

Several potential pathophysiologic phenomena, including "cerebral shutdown," are postulated to be responsible for SUDEP. Since the evidence for a seizure-related mechanism is strong, a poor understanding of the physiology of human seizure termination is a major handicap. However, rather than a failure of a single homeostatic mechanism, such as postictal arousal, it may be a "perfect storm" created by the lining up of a several factors that lead to death.

Entities:  

Year:  2013        PMID: 24348118      PMCID: PMC3854734          DOI: 10.5698/1535-7597-13.5.236

Source DB:  PubMed          Journal:  Epilepsy Curr        ISSN: 1535-7511            Impact factor:   7.500


  33 in total

1.  Autonomic changes with seizures correlate with postictal EEG suppression.

Authors:  M-Z Poh; T Loddenkemper; C Reinsberger; N C Swenson; S Goyal; J R Madsen; R W Picard
Journal:  Neurology       Date:  2012-04-25       Impact factor: 9.910

2.  Postictal generalized electroencephalographic suppression is associated with generalized seizures.

Authors:  Rainer Surges; Adam Strzelczyk; Catherine A Scott; Matthew C Walker; Josemir W Sander
Journal:  Epilepsy Behav       Date:  2011-05-14       Impact factor: 2.937

3.  Postictal generalized EEG suppression is linked to seizure-associated respiratory dysfunction but not postictal apnea.

Authors:  Masud Seyal; Kimberly A Hardin; Lisa M Bateman
Journal:  Epilepsia       Date:  2012-03-20       Impact factor: 5.864

Review 4.  Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms.

Authors:  Rainer Surges; Roland D Thijs; Hanno L Tan; Josemir W Sander
Journal:  Nat Rev Neurol       Date:  2009-08-11       Impact factor: 42.937

5.  An electroclinical case-control study of sudden unexpected death in epilepsy.

Authors:  Samden D Lhatoo; Howard J Faulkner; Krystina Dembny; Kathy Trippick; Claire Johnson; Jonathan M Bird
Journal:  Ann Neurol       Date:  2010-12       Impact factor: 10.422

6.  Postictal central apnea as a cause of SUDEP: evidence from near-SUDEP incident.

Authors:  E L So; M C Sam; T L Lagerlund
Journal:  Epilepsia       Date:  2000-11       Impact factor: 5.864

7.  Serotonin reuptake inhibitors are associated with reduced severity of ictal hypoxemia in medically refractory partial epilepsy.

Authors:  Lisa M Bateman; Chin-Shang Li; Tzu-Chun Lin; Masud Seyal
Journal:  Epilepsia       Date:  2010-10       Impact factor: 5.864

8.  Prevention of seizure-induced sudden death in a chronic SUDEP model by semichronic administration of a selective serotonin reuptake inhibitor.

Authors:  Carl L Faingold; Srinivasan Tupal; Marcus Randall
Journal:  Epilepsy Behav       Date:  2011-07-23       Impact factor: 2.937

9.  Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: report on two deaths in video-EEG-monitored patients.

Authors:  Lisa M Bateman; Mark Spitz; Masud Seyal
Journal:  Epilepsia       Date:  2010-02-03       Impact factor: 5.864

10.  Multiple serotonergic brainstem abnormalities in sudden infant death syndrome.

Authors:  David S Paterson; Felicia L Trachtenberg; Eric G Thompson; Richard A Belliveau; Alan H Beggs; Ryan Darnall; Amy E Chadwick; Henry F Krous; Hannah C Kinney
Journal:  JAMA       Date:  2006-11-01       Impact factor: 56.272

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  8 in total

1.  Serotonin neurones have anti-convulsant effects and reduce seizure-induced mortality.

Authors:  Gordon F Buchanan; Nicholas M Murray; Michael A Hajek; George B Richerson
Journal:  J Physiol       Date:  2014-08-08       Impact factor: 5.182

2.  Decreased heart rate and enhanced sinus arrhythmia during interictal sleep demonstrate autonomic imbalance in generalized epilepsy.

Authors:  Siddharth S Sivakumar; Amalia G Namath; Ingrid E Tuxhorn; Stephen J Lewis; Roberto F Galán
Journal:  J Neurophysiol       Date:  2016-02-17       Impact factor: 2.714

3.  Influence of vigilance state on physiological consequences of seizures and seizure-induced death in mice.

Authors:  Michael A Hajek; Gordon F Buchanan
Journal:  J Neurophysiol       Date:  2016-02-17       Impact factor: 2.714

Review 4.  Serotonin and sudden unexpected death in epilepsy.

Authors:  Alexandra N Petrucci; Katelyn G Joyal; Benton S Purnell; Gordon F Buchanan
Journal:  Exp Neurol       Date:  2019-12-19       Impact factor: 5.330

5.  SUDEP in the North American SUDEP Registry: The full spectrum of epilepsies.

Authors:  Chloe Verducci; Fizza Hussain; Elizabeth Donner; Brian D Moseley; Jeffrey Buchhalter; Dale Hesdorffer; Daniel Friedman; Orrin Devinsky
Journal:  Neurology       Date:  2019-06-19       Impact factor: 9.910

6.  Automated detection of activity onset after postictal generalized EEG suppression.

Authors:  Bishal Lamichhane; Yejin Kim; Santiago Segarra; Guoqiang Zhang; Samden Lhatoo; Jaison Hampson; Xiaoqian Jiang
Journal:  BMC Med Inform Decis Mak       Date:  2020-12-24       Impact factor: 2.796

Review 7.  The role of sleep state and time of day in modulating breathing in epilepsy: implications for sudden unexpected death in epilepsy.

Authors:  Katelyn G Joyal; Benjamin L Kreitlow; Gordon F Buchanan
Journal:  Front Neural Circuits       Date:  2022-08-23       Impact factor: 3.342

8.  Post-ictal Generalized EEG Suppression is reduced by Enhancing Dorsal Raphe Serotonergic Neurotransmission.

Authors:  Alexandra N Petrucci; Katelyn G Joyal; Jonathan W Chou; Rui Li; Kimberly M Vencer; Gordon F Buchanan
Journal:  Neuroscience       Date:  2020-11-24       Impact factor: 3.590

  8 in total

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