Literature DB >> 17117854

"Click to chelate": synthesis and installation of metal chelates into biomolecules in a single step.

Thomas L Mindt1, Harriet Struthers, Luc Brans, Todor Anguelov, Christian Schweinsberg, Veronique Maes, Dirk Tourwé, Roger Schibli.   

Abstract

Click chemistry has been employed for the assembly of novel and efficient triazole-based multidentate chelating systems while simultaneously attaching them to molecules of biological interest. The "click-to-chelate" approach offers a powerful new tool for the modification of (bio)molecules with metal chelators for potential diagnostic and therapeutic applications.

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Year:  2006        PMID: 17117854     DOI: 10.1021/ja066779f

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  27 in total

1.  Clickable bifunctional radiometal chelates for peptide labeling.

Authors:  Artem Y Lebedev; Jason P Holland; Jason S Lewis
Journal:  Chem Commun (Camb)       Date:  2010-02-06       Impact factor: 6.222

2.  Cu(I)-assisted click chemistry strategy for conjugation of non-protected cross-bridged macrocyclic chelators to tumour-targeting peptides.

Authors:  Zhengxin Cai; Barbara T Y Li; Edward H Wong; Gary R Weisman; Carolyn J Anderson
Journal:  Dalton Trans       Date:  2015-03-07       Impact factor: 4.390

Review 3.  Click chemistry, a powerful tool for pharmaceutical sciences.

Authors:  Christopher D Hein; Xin-Ming Liu; Dong Wang
Journal:  Pharm Res       Date:  2008-05-29       Impact factor: 4.200

4.  Integrated and passive 1,2,3-triazolyl groups in fluorescent indicators for zinc(II) ions: thermodynamic and kinetic evaluations.

Authors:  J Tyler Simmons; John R Allen; Deborah R Morris; Ronald J Clark; Cathy W Levenson; Michael W Davidson; Lei Zhu
Journal:  Inorg Chem       Date:  2013-04-26       Impact factor: 5.165

5.  Rhenium and technetium bi- and tricarbonyl complexes in a new strategy for biomolecule incorporation using click chemistry.

Authors:  Thomas R Hayes; Benjamin B Kasten; Charles L Barnes; Paul D Benny
Journal:  Dalton Trans       Date:  2014-04-07       Impact factor: 4.390

Review 6.  Phage display in molecular imaging and diagnosis of cancer.

Authors:  Susan L Deutscher
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

Review 7.  Growing applications of "click chemistry" for bioconjugation in contemporary biomedical research.

Authors:  Kido Nwe; Martin W Brechbiel
Journal:  Cancer Biother Radiopharm       Date:  2009-06       Impact factor: 3.099

8.  Quick assembly of 1,4-diphenyltriazoles as probes targeting beta-amyloid aggregates in Alzheimer's disease.

Authors:  Wenchao Qu; Mei-Ping Kung; Catherine Hou; Shunichi Oya; Hank F Kung
Journal:  J Med Chem       Date:  2007-06-15       Impact factor: 7.446

Review 9.  Cu(I)-catalyzed Huisgen azide-alkyne 1,3-dipolar cycloaddition reaction in nucleoside, nucleotide, and oligonucleotide chemistry.

Authors:  Franck Amblard; Jong Hyun Cho; Raymond F Schinazi
Journal:  Chem Rev       Date:  2009-09       Impact factor: 60.622

10.  H(2)azapa: a versatile acyclic multifunctional chelator for (67)Ga, (64)Cu, (111)In, and (177)Lu.

Authors:  Gwendolyn A Bailey; Eric W Price; Brian M Zeglis; Cara L Ferreira; Eszter Boros; Michael J Lacasse; Brian O Patrick; Jason S Lewis; Michael J Adam; Chris Orvig
Journal:  Inorg Chem       Date:  2012-10-29       Impact factor: 5.165

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