Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Role of miRNAs and epigenetics in neural stem cell fate determination.

Literature DB >> 24342893

Role of miRNAs and epigenetics in neural stem cell fate determination.

Miguel Alejandro Lopez-Ramirez¹, Stefania Nicoli¹.

Abstract

The regulation of gene expression that determines stem cell fate determination is tightly controlled by both epigenetic and posttranscriptional mechanisms. Indeed, small non-coding RNAs such as microRNAs (miRNAs) are able to regulate neural stem cell fate by targeting chromatin-remodeling pathways. Here, we aim to summarize the latest findings regarding the feedback network of epigenetics and miRNAs during embryonic and adult neurogenesis.

Entities: Disease

Keywords: cell fate determination; epigenetics machinery; microRNAs; neural stem cells; neurogenesis

Mesh：

Substances：
MicroRNAs

Year: 2013 PMID： 24342893 PMCID： PMC3928190 DOI： 10.4161/epi.27536

Source DB: PubMed Journal: Epigenetics ISSN： 1559-2294 Impact factor: 4.528

142 in total

1. MicroRNA genes are transcribed by RNA polymerase II.

Authors: Yoontae Lee; Minju Kim; Jinju Han; Kyu-Hyun Yeom; Sanghyuk Lee; Sung Hee Baek; V Narry Kim
Journal: EMBO J Date: 2004-09-16 Impact factor: 11.598

2. The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing.

Authors: Eugene V Makeyev; Jiangwen Zhang; Monica A Carrasco; Tom Maniatis
Journal: Mol Cell Date: 2007-08-03 Impact factor: 17.970

Review 3. Radial glia and neural stem cells.

Authors: Paolo Malatesta; Irene Appolloni; Filippo Calzolari
Journal: Cell Tissue Res Date: 2007-09-11 Impact factor: 5.249

4. microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus.

Authors: Stephen T Magill; Xiaolu A Cambronne; Bryan W Luikart; Daniel T Lioy; Barbara H Leighton; Gary L Westbrook; Gail Mandel; Richard H Goodman
Journal: Proc Natl Acad Sci U S A Date: 2010-11-08 Impact factor: 11.205

5. DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain.

Authors: T Takizawa; K Nakashima; M Namihira; W Ochiai; A Uemura; M Yanagisawa; N Fujita; M Nakao; T Taga
Journal: Dev Cell Date: 2001-12 Impact factor: 12.270

6. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex.

Authors: João D Pereira; Stephen N Sansom; James Smith; Marc-Werner Dobenecker; Alexander Tarakhovsky; Frederick J Livesey
Journal: Proc Natl Acad Sci U S A Date: 2010-08-23 Impact factor: 11.205

7. MicroRNA-124 is a subventricular zone neuronal fate determinant.

Authors: Malin Åkerblom; Rohit Sachdeva; Isabelle Barde; Sonia Verp; Bernhard Gentner; Didier Trono; Johan Jakobsson
Journal: J Neurosci Date: 2012-06-27 Impact factor: 6.167

8. An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP.

Authors: Gary A Wayman; Monika Davare; Hideaki Ando; Dale Fortin; Olga Varlamova; Hai-Ying M Cheng; Daniel Marks; Karl Obrietan; Thomas R Soderling; Richard H Goodman; Soren Impey
Journal: Proc Natl Acad Sci U S A Date: 2008-06-24 Impact factor: 11.205

9. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells.

Authors: Xuekun Li; Basam Z Barkho; Yuping Luo; Richard D Smrt; Nicholas J Santistevan; Changmei Liu; Tomoko Kuwabara; Fred H Gage; Xinyu Zhao
Journal: J Biol Chem Date: 2008-08-08 Impact factor: 5.157

10. Dicer is essential for mouse development.

Authors: Emily Bernstein; Sang Yong Kim; Michelle A Carmell; Elizabeth P Murchison; Heather Alcorn; Mamie Z Li; Alea A Mills; Stephen J Elledge; Kathryn V Anderson; Gregory J Hannon
Journal: Nat Genet Date: 2003-10-05 Impact factor: 38.330

19 in total

Review 1. Epigenetic regulation of early neural fate commitment.

Authors: Yunbo Qiao; Xianfa Yang; Naihe Jing
Journal: Cell Mol Life Sci Date: 2016-01-22 Impact factor: 9.261

2. MicroRNA-765 regulates neural stem cell proliferation and differentiation by modulating Hes1 expression.

Authors: Siou Li; Weina Zhao; Qing Xu; Yang Yu; Changhao Yin
Journal: Am J Transl Res Date: 2016-07-15 Impact factor: 4.060

Review 3. Turing Revisited: Decoding the microRNA Messages in Brain Extracellular Vesicles for Early Detection of Neurodevelopmental Disorders.

Authors: Virginie Gillet; Darel John Hunting; Larissa Takser
Journal: Curr Environ Health Rep Date: 2016-09

Role of miRNAs and epigenetics in neural stem cell fate determination.

1. MicroRNA genes are transcribed by RNA polymerase II.

2. The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing.

Review 3. Radial glia and neural stem cells.

4. microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus.

5. DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain.

6. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex.

7. MicroRNA-124 is a subventricular zone neuronal fate determinant.

8. An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP.

9. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells.

10. Dicer is essential for mouse development.

Review 1. Epigenetic regulation of early neural fate commitment.

2. MicroRNA-765 regulates neural stem cell proliferation and differentiation by modulating Hes1 expression.

Review 3. Turing Revisited: Decoding the microRNA Messages in Brain Extracellular Vesicles for Early Detection of Neurodevelopmental Disorders.

4. Epigenetic actions of environmental factors and promising drugs for cancer therapy.

Review 5. Environmental alterations of epigenetics prior to the birth.

6. AKT Isoforms in the Immune Response in Cancer.

7. A Dicer-miR-107 Interaction Regulates Biogenesis of Specific miRNAs Crucial for Neurogenesis.

8. miR-381 Regulates Neural Stem Cell Proliferation and Differentiation via Regulating Hes1 Expression.

Review 9. Neurogenesis in the embryonic and adult brain: same regulators, different roles.

10. In vivo mutagenesis of miRNA gene families using a scalable multiplexed CRISPR/Cas9 nuclease system.