Literature DB >> 24338720

CCX-CKR expression in colorectal cancer and patient survival.

Yunxiang Zhu1, Wentao Tang, Yun Liu, Guanghui Wang, Zhonglin Liang, Long Cui.   

Abstract

Colorectal cancer is one of the most common malignant cancers, with bad prognosis when distal metastasis occurs. The current study aimed to investigate the potential value of using CCX-CKR expression for the prognosis of colorectal cancer patients. The results showed that CCX-CKR expression was a negative predictor of cancer metastasis, and that it was positively correlated to the patients’ survival rate. Finally, we found that CCX-CKR expression in vitro could modulate cellular migration and invasion abilities, potentially via the regulation of other chemotactic factors/receptors.

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Year:  2014        PMID: 24338720     DOI: 10.5301/jbm.5000057

Source DB:  PubMed          Journal:  Int J Biol Markers        ISSN: 0393-6155            Impact factor:   2.659


  4 in total

1.  ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity.

Authors:  Matteo Massara; Ornella Bonavita; Benedetta Savino; Nicoletta Caronni; Valeria Mollica Poeta; Marina Sironi; Elisa Setten; Camilla Recordati; Laura Crisafulli; Francesca Ficara; Alberto Mantovani; Massimo Locati; Raffaella Bonecchi
Journal:  Nat Commun       Date:  2018-02-14       Impact factor: 14.919

Review 2.  The Role of Selected Chemokines and Their Receptors in the Development of Gliomas.

Authors:  Magdalena Groblewska; Ala Litman-Zawadzka; Barbara Mroczko
Journal:  Int J Mol Sci       Date:  2020-05-24       Impact factor: 5.923

Review 3.  Chemokines and Chemokine Receptors: New Targets for Cancer Immunotherapy.

Authors:  Valeria Mollica Poeta; Matteo Massara; Arianna Capucetti; Raffaella Bonecchi
Journal:  Front Immunol       Date:  2019-03-06       Impact factor: 7.561

4.  Biphasic Expression of Atypical Chemokine Receptor (ACKR) 2 and ACKR4 in Colorectal Neoplasms in Association with Histopathological Findings.

Authors:  Paulina Lewandowska; Jaroslaw Wierzbicki; Marek Zawadzki; Anil Agrawal; Małgorzata Krzystek-Korpacka
Journal:  Biomolecules       Date:  2020-12-23
  4 in total

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