Literature DB >> 24338636

Rational design of polyion complex nanoparticles to overcome cisplatin resistance in cancer therapy.

Xian-Zhu Yang1, Xiao-Jiao Du, Yang Liu, Yan-Hua Zhu, Yang-Zhong Liu, Ya-Ping Li, Jun Wang.   

Abstract

Rationally designed PIC nanoparticles as next-generation delivery system: we have developed a core-shell-corona PIC nanoparticle (⊕) NP/Pt@PPC-DA as a next-generation delivery system. (⊕) NP/Pt@PPC-DA exhibits prolonged circulation and enhanced drug accumulation in tumors. Subsequently, tumor pH leads to the release of (⊕) NP/Pt, which facilitates cellular uptake followed by rapid intracellular cisplatin release. Using this delivery strategy cisplatin-resistant tumor growth in a murine xenograft model has been successfully suppressed.
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  PIC nanoparticles; cisplatin resistance; drug delivery; tumor pH-responsive

Mesh：

Substances：

Year:  2013        PMID： 24338636     DOI： 10.1002/adma.201303360

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  10 in total

1.  Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy.

Authors:  Chenggen Qian; Jicheng Yu; Yulei Chen; Quanyin Hu; Xuanzhong Xiao; Wujin Sun; Chao Wang; Peijian Feng; Qun-Dong Shen; Zhen Gu
Journal:  Adv Mater       Date:  2016-03-07       Impact factor: 30.849

Review 2.  Novel delivery approaches for cancer therapeutics.

Authors:  Ashim K Mitra; Vibhuti Agrahari; Abhirup Mandal; Kishore Cholkar; Chandramouli Natarajan; Sujay Shah; Mary Joseph; Hoang M Trinh; Ravi Vaishya; Xiaoyan Yang; Yi Hao; Varun Khurana; Dhananjay Pal
Journal:  J Control Release       Date:  2015-10-09       Impact factor: 9.776

3.  Adjudin-loaded redox-sensitive paclitaxel-prodrug micelles for overcoming multidrug resistance with efficient targeted Colon cancer therapy.

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Journal:  Drug Deliv       Date:  2020-12       Impact factor: 6.419

4.  A Method to Encapsulate Small Organic Molecules in Calcium Phosphate Nanoparticles Based on the Supramolecular Chemistry of Cyclodextrin.

Authors:  Zhongming Zhu; Feng Li; Fei Zhong; Kang Zhai; Wei Tao; Gengyun Sun
Journal:  Micromachines (Basel)       Date:  2017-09-27       Impact factor: 2.891

5.  Anticancer Properties of Platinum Nanoparticles and Retinoic Acid: Combination Therapy for the Treatment of Human Neuroblastoma Cancer.

Authors:  Sangiliyandi Gurunathan; Muniyandi Jeyaraj; Min-Hee Kang; Jin-Hoi Kim
Journal:  Int J Mol Sci       Date:  2020-09-16       Impact factor: 5.923

Review 6.  The Smart Drug Delivery System and Its Clinical Potential.

Authors:  Dong Liu; Fang Yang; Fei Xiong; Ning Gu
Journal:  Theranostics       Date:  2016-06-07       Impact factor: 11.556

7.  Design of Tumor Acidity-Responsive Sheddable Nanoparticles for Fluorescence/Magnetic Resonance Imaging-Guided Photodynamic Therapy.

Authors:  Feng Fan; Yue Yu; Fei Zhong; Meng Gao; Tianmeng Sun; Jiaxin Liu; Huimao Zhang; Haisheng Qian; Wei Tao; Xianzhu Yang
Journal:  Theranostics       Date:  2017-03-07       Impact factor: 11.556

8.  Construction of versatile multilayered composite nanoparticles from a customized nanogel template.

Authors:  Jian Zhang; Jinpeng Jia; Jimin P Kim; Fei Yang; Xing Wang; Hong Shen; Sijia Xu; Jian Yang; Decheng Wu
Journal:  Bioact Mater       Date:  2017-07-01

9.  Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9+ T cells.

Authors:  Hongmei Chen; Xiuxiu Cong; Chenxi Wu; Xuan Wu; Jialiang Wang; Kuirong Mao; Jie Li; Ge Zhu; Feiqi Liu; Xiandi Meng; Jia Song; Xu Sun; Xin Wang; Shuhan Liu; Shi Zhang; Xianzhu Yang; Yanqiu Song; Yong-Guang Yang; Tianmeng Sun
Journal:  Sci Adv       Date:  2020-01-29       Impact factor: 14.136

10.  Enhanced anticancer effect of doxorubicin by TPGS-coated liposomes with Bcl-2 siRNA-corona for dual suppression of drug resistance.

Authors:  Yinghuan Li; Xi Tan; Xuhan Liu; Lingyan Liu; Yan Fang; Rong Rao; Yuanyuan Ren; Xiangliang Yang; Wei Liu
Journal:  Asian J Pharm Sci       Date:  2019-11-12       Impact factor: 6.598
  10 in total

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