Literature DB >> 24332035

Location, location, location: macrophage positioning within tumors determines pro- or antitumor activity.

Lee B Rivera1, Gabriele Bergers2.   

Abstract

Macrophages infiltrate hypoxic tumor regions, where they promote angiogenesis and immunosuppression. In this issue of Cancer Cell, Casazza and colleagues report that tumor-associated macrophage (TAM) entry into avascular tumor areas is regulated by Semaphorin 3A/Neuropilin-1 signaling; interference with this pathway entraps TAMs in oxygenated areas, preventing their tumorigenic function.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 24332035      PMCID： PMC4243836          DOI： 10.1016/j.ccr.2013.11.014

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  10 in total

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Authors:  Bin-Zhi Qian; Jeffrey W Pollard
Journal:  Cell       Date:  2010-04-02       Impact factor: 41.582

2.  Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth.

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Journal:  Cancer Cell       Date:  2007-01       Impact factor: 31.743

3.  Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy.

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Journal:  Cancer Cell       Date:  2013-10-24       Impact factor: 31.743

4.  The good and bad of microglia/macrophages: new hope in stroke therapeutics.

Authors:  Ya-chi Huang; Zhong-ping Feng
Journal:  Acta Pharmacol Sin       Date:  2012-12-24       Impact factor: 6.150

5.  Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity.

Authors:  Andrea Casazza; Damya Laoui; Mathias Wenes; Sabrina Rizzolio; Nicklas Bassani; Marco Mambretti; Sofie Deschoemaeker; Jo A Van Ginderachter; Luca Tamagnone; Massimiliano Mazzone
Journal:  Cancer Cell       Date:  2013-12-09       Impact factor: 31.743

Review 6.  Neutralizing tumor-promoting chronic inflammation: a magic bullet?

Authors:  Lisa M Coussens; Laurence Zitvogel; A Karolina Palucka
Journal:  Science       Date:  2013-01-18       Impact factor: 47.728

Review 7.  The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance.

Authors:  Paola Allavena; Antonio Sica; Cecilia Garlanda; Alberto Mantovani
Journal:  Immunol Rev       Date:  2008-04       Impact factor: 12.988

Review 8.  Macrophage regulation of tumor responses to anticancer therapies.

Authors:  Michele De Palma; Claire E Lewis
Journal:  Cancer Cell       Date:  2013-03-18       Impact factor: 31.743

9.  Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.

Authors:  Damya Laoui; Eva Van Overmeire; Giusy Di Conza; Chiara Aldeni; Jiri Keirsse; Yannick Morias; Kiavash Movahedi; Isabelle Houbracken; Elio Schouppe; Yvon Elkrim; Oussama Karroum; Bénédicte Jordan; Peter Carmeliet; Conny Gysemans; Patrick De Baetselier; Massimiliano Mazzone; Jo A Van Ginderachter
Journal:  Cancer Res       Date:  2013-11-12       Impact factor: 12.701

Review 10.  The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies.

Authors:  L Bingle; N J Brown; Claire E Lewis
Journal:  J Pathol       Date:  2002-03       Impact factor: 7.996
  10 in total
  26 in total

Review 1.  Regulation of Blood and Lymphatic Vessels by Immune Cells in Tumors and Metastasis.

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Journal:  Annu Rev Physiol       Date:  2019-02-10       Impact factor: 19.318

2.  CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10.

Authors:  Ian H Guldner; Qingfei Wang; Lin Yang; Samantha M Golomb; Zhuo Zhao; Jacqueline A Lopez; Abigail Brunory; Erin N Howe; Yizhe Zhang; Bhavana Palakurthi; Martin Barron; Hongyu Gao; Xiaoling Xuei; Yunlong Liu; Jun Li; Danny Z Chen; Gary E Landreth; Siyuan Zhang
Journal:  Cell       Date:  2020-10-27       Impact factor: 41.582

3.  Heparanase is required for activation and function of macrophages.

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Journal:  Proc Natl Acad Sci U S A       Date:  2016-11-14       Impact factor: 11.205

4.  CD4+ T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4+ T cells in pancreatic cancer development.

Authors:  Lisa Goebel; Evelin Grage-Griebenow; Artur Gorys; Ole Helm; Geeske Genrich; Lennart Lenk; Daniela Wesch; Hendrik Ungefroren; Sandra Freitag-Wolf; Bence Sipos; Christoph Röcken; Heiner Schäfer; Susanne Sebens
Journal:  Oncoimmunology       Date:  2015-01-22       Impact factor: 8.110

5.  M1 and M2: there is no "good" and "bad"-How macrophages promote malignancy-associated features in tumorigenesis.

Authors:  Ole Helm; Janka Held-Feindt; Heiner Schäfer; Susanne Sebens
Journal:  Oncoimmunology       Date:  2014-07-03       Impact factor: 8.110

Review 6.  Physiological, Tumor, and Metastatic Niches: Opportunities and Challenges for Targeting the Tumor Microenvironment.

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Journal:  Crit Rev Oncog       Date:  2015

Review 7.  The reciprocal function and regulation of tumor vessels and immune cells offers new therapeutic opportunities in cancer.

Authors:  Rindert Missiaen; Massimiliano Mazzone; Gabriele Bergers
Journal:  Semin Cancer Biol       Date:  2018-06-20       Impact factor: 15.707

8.  CTHRC1 promotes liver metastasis by reshaping infiltrated macrophages through physical interactions with TGF-β receptors in colorectal cancer.

Authors:  Xue-Li Zhang; Li-Peng Hu; Qin Yang; Wei-Ting Qin; Xu Wang; Chun-Jie Xu; Guang-Ang Tian; Xiao-Mei Yang; Lin-Li Yao; Lei Zhu; Hui-Zhen Nie; Qing Li; Qing Xu; Zhi-Gang Zhang; Yan-Li Zhang; Jun Li; Ya-Hui Wang; Shu-Heng Jiang
Journal:  Oncogene       Date:  2021-05-13       Impact factor: 9.867

9.  Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker.

Authors:  Andrew X Chen; Robyn D Gartrell; Junfei Zhao; Pavan S Upadhyayula; Wenting Zhao; Jinzhou Yuan; Hanna E Minns; Athanassios Dovas; Jeffrey N Bruce; Anna Lasorella; Antonio Iavarone; Peter Canoll; Peter A Sims; Raul Rabadan
Journal:  Genome Med       Date:  2021-05-19       Impact factor: 11.117

Review 10.  Impact of Immunometabolism on Cancer Metastasis: A Focus on T Cells and Macrophages.

Authors:  Nina C Flerin; Sotiria Pinioti; Alessio Menga; Alessandra Castegna; Massimiliano Mazzone
Journal:  Cold Spring Harb Perspect Med       Date:  2020-09-01       Impact factor: 5.159
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