Literature DB >> 24328424

Vogt-Koyanagi-Harada disease: clinical and demographic characteristics of patients in a specialized eye hospital in Turkey.

Pinar Ozdal1, Yasemin Ozdamar, Alper Yazici, Mehmet Y Teke, Faruk Ozturk.   

Abstract

PURPOSE: To evaluate clinical and demographic features of Vogt-Kayanagi-Harada disease (VKH) disease in Turkish patients and compare them with previously published data.
METHODS: Demographic and clinical features of 32 patients diagnosed as VKH in a tertiary referral center were retrospectively reviewed.
RESULTS: The mean age at presentation was 33.6 ± 10.4 years. Seventy-five percent of the patients were female and 62.5% of the patients presented during the last 2 years. The disease was complete in 31.2%, incomplete in 50%, and probable in 18.8% of the patients. The clinical course was acute in 50%, chronic recurrent in 34.4%, and chronic in 15.6%. The most common findings were bilateral serous retinal detachment ± papillitis in acute cases and retinal pigment epithelial changes of the macula in chronic cases.
CONCLUSIONS: Although rare in Turkey, VKH disease seems to have increased during the last few years. The disease is incomplete and acute in half of the patients and has a quite good visual prognosis.

Entities:  

Keywords:  Ocular involvement; VKH; Vogt-Koyanagi-Harada disease; treatment; uveitis

Mesh:

Year:  2013        PMID: 24328424     DOI: 10.3109/09273948.2013.856448

Source DB:  PubMed          Journal:  Ocul Immunol Inflamm        ISSN: 0927-3948            Impact factor:   3.070


  4 in total

1.  The spectrum of Vogt-Koyanagi-Harada disease in Iran.

Authors:  Alireza Hedayatfar; Seyedeh Maryam Hosseini; Nasser Karimi; Khalil Ghasemi Falavarjani; Negin Badie; Mahsa Zameni; Masoud Soheilian
Journal:  Int Ophthalmol       Date:  2017-03-04       Impact factor: 2.031

2.  "Revised diagnostic criteria" for Vogt-Koyanagi-Harada disease fail to improve disease management.

Authors:  Alireza Hedayatfar; Sana Khochtali; Moncef Khairallah; Masaru Takeuchi; Ahmed Abu El Asrar; Carl P Herbort
Journal:  J Curr Ophthalmol       Date:  2018-12-13

Review 3.  Vogt-Koyanagi-Harada is a Curable Autoimmune Disease: Early Diagnosis and Immediate Dual Steroidal and Non-Steroidal Immunosuppression are Crucial Prerequisites.

Authors:  Ioannis Papasavvas; Ilknur Tugal-Tutkun; Carl P Herbort
Journal:  J Curr Ophthalmol       Date:  2020-12-12

Review 4.  Vogt-Koyanagi-Harada disease: review of a rare autoimmune disease targeting antigens of melanocytes.

Authors:  Marcelo Mendes Lavezzo; Viviane Mayumi Sakata; Celso Morita; Ever Ernesto Caso Rodriguez; Smairah Frutuoso Abdallah; Felipe T G da Silva; Carlos Eduardo Hirata; Joyce Hisae Yamamoto
Journal:  Orphanet J Rare Dis       Date:  2016-03-24       Impact factor: 4.123

  4 in total

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