Literature DB >> 24316776

The NCGENES project: exploring the new world of genome sequencing.

Ann Katherine M Foreman1, Kristy Lee, James P Evans.   

Abstract

Massively parallel sequencing (MPS) is now a clinical reality, promising improved diagnosis, targeted therapies, and population-based screening. To realize the potential of genomics, we must learn how to apply this technology optimally. The NCGENES project is designed to address several challenges that must be overcome in order to integrate MPS into clinical care.

Entities:  

Mesh：

Year:  2013        PMID： 24316776

Source DB:  PubMed          Journal:  N C Med J        ISSN： 0029-2559


  14 in total

1.  Which Results to Return: Subjective Judgments in Selecting Medically Actionable Genes.

Authors:  Gabriel Lázaro-Muñoz; John M Conley; Arlene M Davis; Anya E R Prince; R Jean Cadigan
Journal:  Genet Test Mol Biomarkers       Date:  2017-02-01

2.  Looking for Trouble: Preventive Genomic Sequencing in the General Population and the Role of Patient Choice.

Authors:  Gabriel Lázaro-Muñoz; John M Conley; Arlene M Davis; Marcia Van Riper; Rebecca L Walker; Eric T Juengst
Journal:  Am J Bioeth       Date:  2015       Impact factor: 11.229

3.  Flexible positions, managed hopes: the promissory bioeconomy of a whole genome sequencing cancer study.

Authors:  Rachel Haase; Marsha Michie; Debra Skinner
Journal:  Soc Sci Med       Date:  2015-02-13       Impact factor: 4.634

4.  Psychological adaptation to diagnostic genomic sequencing results: The role of hope fulfillment.

Authors:  Ida Griesemer; Elizabeth Moore; Cynthia Khan; Myra Roche; Gail Henderson; Christine Rini
Journal:  Health Psychol       Date:  2019-04-08       Impact factor: 4.267

5.  Testing and extending strategies for identifying genetic disease-related encounters in pediatric patients.

Authors:  Lisa P Spees; Karen Hicklin; Michael C Adams; Laura Farnan; Jeannette T Bensen; Donna B Gilleskie; Jonathan S Berg; Bradford C Powell; Kristen Hassmiller Lich
Journal:  Genet Med       Date:  2022-01-13       Impact factor: 8.864

6.  Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC.

Authors:  Xiaobei Zhao; Anyou Wang; Vonn Walter; Nirali M Patel; David A Eberhard; Michele C Hayward; Ashley H Salazar; Heejoon Jo; Matthew G Soloway; Matthew D Wilkerson; Joel S Parker; Xiaoying Yin; Guosheng Zhang; Marni B Siegel; Gary B Rosson; H Shelton Earp; Norman E Sharpless; Margaret L Gulley; Karen E Weck; D Neil Hayes; Stergios J Moschos
Journal:  PLoS One       Date:  2015-06-15       Impact factor: 3.240

7.  The who, what, and why of research participants' intentions to request a broad range of secondary findings in a diagnostic genomic sequencing study.

Authors:  Christine Rini; Cynthia M Khan; Elizabeth Moore; Myra I Roche; James P Evans; Jonathan S Berg; Bradford C Powell; Giselle Corbie-Smith; Ann Katherine M Foreman; Ida Griesemer; Kristy Lee; Julianne M O'Daniel; Gail E Henderson
Journal:  Genet Med       Date:  2017-10-26       Impact factor: 8.822

8.  Evaluating the clinical utility of early exome sequencing in diverse pediatric outpatient populations in the North Carolina Clinical Genomic Evaluation of Next-generation Exome Sequencing (NCGENES) 2 study: a randomized controlled trial.

Authors:  Jonathan S Berg; Jeannette T Bensen; Brooke S Staley; Laura V Milko; Margaret Waltz; Ida Griesemer; Lonna Mollison; Tracey L Grant; Laura Farnan; Myra Roche; Angelo Navas; Alexandra Lightfoot; Ann Katherine M Foreman; Julianne M O'Daniel; Suzanne C O'Neill; Feng-Chang Lin; Tamara S Roman; Alicia Brandt; Bradford C Powell; Christine Rini
Journal:  Trials       Date:  2021-06-14       Impact factor: 2.279

9.  Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing.

Authors:  Dayne L Filer; Fengshen Kuo; Alicia T Brandt; Christian R Tilley; Piotr A Mieczkowski; Jonathan S Berg; Kimberly Robasky; Yun Li; Chris Bizon; Jeffery L Tilson; Bradford C Powell; Darius M Bost; Clark D Jeffries; Kirk C Wilhelmsen
Journal:  BMC Bioinformatics       Date:  2021-07-20       Impact factor: 3.169

10.  Secondary findings from clinical genomic sequencing: prevalence, patient perspectives, family history assessment, and health-care costs from a multisite study.

Authors:  David L Veenstra; Jonathan S Berg; Robert C Green; Leslie G Biesecker; Lucia A Hindorff; M Ragan Hart; Barbara B Biesecker; Carrie L Blout; Kurt D Christensen; Laura M Amendola; Katie L Bergstrom; Sawona Biswas; Kevin M Bowling; Kyle B Brothers; Laura K Conlin; Greg M Cooper; Matthew C Dulik; Kelly M East; Jessica N Everett; Candice R Finnila; Arezou A Ghazani; Marian J Gilmore; Katrina A B Goddard; Gail P Jarvik; Jennifer J Johnston; Tia L Kauffman; Whitley V Kelley; Joel B Krier; Katie L Lewis; Amy L McGuire; Carmit McMullen; Jeffrey Ou; Sharon E Plon; Heidi L Rehm; C Sue Richards; Edward J Romasko; Ane Miren Sagardia; Nancy B Spinner; Michelle L Thompson; Erin Turbitt; Jason L Vassy; Benjamin S Wilfond
Journal:  Genet Med       Date:  2018-10-05       Impact factor: 8.822
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.