Literature DB >> 24315457

Refining a Jagged edge.

Stephen C Blacklow1.   

Abstract

In a recent Cell Reports article, Chillakuri and colleagues showed that the N-terminal "MNNL" domain of the essential Notch ligand Jagged1 resembles a C2 domain and relies on calcium binding to facilitate productive signal transduction.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 24315457      PMCID: PMC3892149          DOI: 10.1016/j.str.2013.11.001

Source DB:  PubMed          Journal:  Structure        ISSN: 0969-2126            Impact factor:   5.006


  10 in total

1.  Structure-function analysis of delta trafficking, receptor binding and signaling in Drosophila.

Authors:  Annette L Parks; Jane R Stout; Scott B Shepard; Kristin M Klueg; Ana A Dos Santos; Todd R Parody; Martina Vaskova; Marc A T Muskavitch
Journal:  Genetics       Date:  2006-10-08       Impact factor: 4.562

Review 2.  Membrane recognition by phospholipid-binding domains.

Authors:  Mark A Lemmon
Journal:  Nat Rev Mol Cell Biol       Date:  2008-02       Impact factor: 94.444

Review 3.  The canonical Notch signaling pathway: unfolding the activation mechanism.

Authors:  Raphael Kopan; Maria Xenia G Ilagan
Journal:  Cell       Date:  2009-04-17       Impact factor: 41.582

4.  Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.

Authors:  Marie Blanke Andrawes; Xiang Xu; Hong Liu; Scott B Ficarro; Jarrod A Marto; Jon C Aster; Stephen C Blacklow
Journal:  J Biol Chem       Date:  2013-07-09       Impact factor: 5.157

5.  Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

Authors:  K Shimizu; S Chiba; K Kumano; N Hosoya; T Takahashi; Y Kanda; Y Hamada; Y Yazaki; H Hirai
Journal:  J Biol Chem       Date:  1999-11-12       Impact factor: 5.157

Review 6.  Notch signaling in leukemia.

Authors:  Jon C Aster; Warren S Pear; Stephen C Blacklow
Journal:  Annu Rev Pathol       Date:  2008       Impact factor: 23.472

Review 7.  Notch signalling: a simple pathway becomes complex.

Authors:  Sarah J Bray
Journal:  Nat Rev Mol Cell Biol       Date:  2006-09       Impact factor: 94.444

Review 8.  Notch receptor-ligand binding and activation: insights from molecular studies.

Authors:  Chandramouli R Chillakuri; Devon Sheppard; Susan M Lea; Penny A Handford
Journal:  Semin Cell Dev Biol       Date:  2012-02-04       Impact factor: 7.727

9.  A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition.

Authors:  Jemima Cordle; Steven Johnson; Joyce Zi Yan Tay; Pietro Roversi; Marian B Wilkin; Beatriz Hernández de Madrid; Hideyuki Shimizu; Sacha Jensen; Pat Whiteman; Boquan Jin; Christina Redfield; Martin Baron; Susan M Lea; Penny A Handford
Journal:  Nat Struct Mol Biol       Date:  2008-07-27       Impact factor: 15.369

10.  Structural analysis uncovers lipid-binding properties of Notch ligands.

Authors:  Chandramouli R Chillakuri; Devon Sheppard; Ma Xenia G Ilagan; Laurie R Holt; Felicity Abbott; Shaoyan Liang; Raphael Kopan; Penny A Handford; Susan M Lea
Journal:  Cell Rep       Date:  2013-11-14       Impact factor: 9.423

  10 in total

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