| Literature DB >> 24309507 |
Shams Tabrez1, Medha Priyadarshini2, Shubha Priyamvada3, Mohd Shahnawaz Khan4, Arivarasu Na3, Syed Kashif Zaidi5.
Abstract
Cancer is a complex disease involving a sequence of gene-environment interactions. Lifestyle, genetics, dietary factors, and environmental pollutants can increase the risk of cancer. Gene-environment interactions have been studied by a candidate-gene approach focusing on metabolism, DNA repair, and apoptosis. Here, we review the influence of gene-environment interactions in carcinogenesis, with emphasis on heavy metal and pesticide exposures.Entities:
Keywords: Environment; Gene; Heavy metals; Pesticides; Polymorphism
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Year: 2013 PMID: 24309507 DOI: 10.1016/j.mrgentox.2013.11.002
Source DB: PubMed Journal: Mutat Res Genet Toxicol Environ Mutagen ISSN: 1383-5718 Impact factor: 2.873