Literature DB >> 24307392

And the winner is...azadithiolate: an amine proton relay in the [FeFe] hydrogenases.

David Schilter1, Thomas B Rauchfuss.   

Abstract

A victory in the pocket: An international team of chemists and biophysicists have resolved the long-standing question of the structure of the active site of the [FeFe] hydrogenases by assembling the active enzyme with a version of the active site synthesized in vitro (see scheme; HydF is a scaffold protein, HydA1 is a natural hydrogenase). The protein incorporating the diiron complex 2 showed similar activity to that of the natural enzyme.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cofactors; enzymology; hydrogen; hydrogenases; iron

Year:  2013        PMID： 24307392      PMCID： PMC4360873          DOI： 10.1002/anie.201307132

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  10 in total

Review 1.  Emerging paradigms for complex iron-sulfur cofactor assembly and insertion.

Authors:  John W Peters; Joan B Broderick
Journal:  Annu Rev Biochem       Date:  2012-04-05       Impact factor: 23.643

Review 2.  Structural and functional analogues of the active sites of the [Fe]-, [NiFe]-, and [FeFe]-hydrogenases.

Authors:  Cédric Tard; Christopher J Pickett
Journal:  Chem Rev       Date:  2009-06       Impact factor: 60.622

3.  Iron carbonyl sulfides, formaldehyde, and amines condense to give the proposed azadithiolate cofactor of the Fe-only hydrogenases.

Authors:  Hongxiang Li; Thomas B Rauchfuss
Journal:  J Am Chem Soc       Date:  2002-02-06       Impact factor: 15.419

4.  Biomimetic assembly and activation of [FeFe]-hydrogenases.

Authors:  A Adamska; C Lambertz; T R Simmons; G Berggren; J Esselborn; M Atta; S Gambarelli; J M Mouesca; E Reijerse; W Lubitz; T Happe; V Artero; M Fontecave
Journal:  Nature       Date:  2013-06-26       Impact factor: 49.962

5.  Infrared studies of the CO-inhibited form of the Fe-only hydrogenase from Clostridium pasteurianum I: examination of its light sensitivity at cryogenic temperatures.

Authors:  Zhujun Chen; Brian J Lemon; Shan Huang; Derrick J Swartz; John W Peters; Kimberly A Bagley
Journal:  Biochemistry       Date:  2002-02-12       Impact factor: 3.162

6.  Crystallographic and FTIR spectroscopic evidence of changes in Fe coordination upon reduction of the active site of the Fe-only hydrogenase from Desulfovibrio desulfuricans.

Authors:  Y Nicolet; A L de Lacey; X Vernède; V M Fernandez; E C Hatchikian; J C Fontecilla-Camps
Journal:  J Am Chem Soc       Date:  2001-02-28       Impact factor: 15.419

7.  An iron complex with pendent amines as a molecular electrocatalyst for oxidation of hydrogen.

Authors:  Tianbiao Liu; Daniel L Dubois; R Morris Bullock
Journal:  Nat Chem       Date:  2013-02-17       Impact factor: 24.427

8.  (14)N HYSCORE investigation of the H-cluster of [FeFe] hydrogenase: evidence for a nitrogen in the dithiol bridge.

Authors:  Alexey Silakov; Brian Wenk; Eduard Reijerse; Wolfgang Lubitz
Journal:  Phys Chem Chem Phys       Date:  2009-06-09       Impact factor: 3.676

9.  Synthetic models for the active site of the [FeFe]-hydrogenase: catalytic proton reduction and the structure of the doubly protonated intermediate.

Authors:  Maria E Carroll; Bryan E Barton; Thomas B Rauchfuss; Patrick J Carroll
Journal:  J Am Chem Soc       Date:  2012-11-05       Impact factor: 15.419

10.  Spontaneous activation of [FeFe]-hydrogenases by an inorganic [2Fe] active site mimic.

Authors:  Camilla Lambertz; Agnieszka Adamska-Venkates; Trevor Simmons; Julian Esselborn; Gustav Berggren; Jens Noth; Judith Siebel; Anja Hemschemeier; Vincent Artero; Edward Reijerse; Marc Fontecave; Wolfgang Lubitz; Thomas Happe
Journal:  Nat Chem Biol       Date:  2013-08-11       Impact factor: 15.040
  10 in total
  2 in total

Review 1.  Overview of the Maturation Machinery of the H-Cluster of [FeFe]-Hydrogenases with a Focus on HydF.

Authors:  Marco Bortolus; Paola Costantini; Davide Doni; Donatella Carbonera
Journal:  Int J Mol Sci       Date:  2018-10-11       Impact factor: 5.923

2.  Hydrogenase Mimics in M12 L24 Nanospheres to Control Overpotential and Activity in Proton-Reduction Catalysis.

Authors:  Riccardo Zaffaroni; Nicole Orth; Ivana Ivanović-Burmazović; Joost N H Reek
Journal:  Angew Chem Int Ed Engl       Date:  2020-08-17       Impact factor: 16.823
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.