Literature DB >> 24302663

Werner's syndrome: incidental finding during pregnancy.

A R Hurtarte Sandoval1, J D Penate Dardón, B J Flores Robles, S Porres.   

Abstract

Werner's syndrome (WS) is a rare autosomal recessive disorder, characterised by skin changes prematurely during adolescence. An unusual case of WS was found in a 27-year-old pregnant woman who presented to the hospital with a history of uncontrolled hypertension at 32 weeks of gestation. All clinical features corresponding to WS (early aging of skin, hair loss, blurred vision and diabetes type 2) appeared to match with the prospective diagnosis, which was confirmed later with genetic testing. The pregnancy became complicated due to oligohydramnios and therefore a caesarean section was carried out in order to preserve the fetus. Despite all implemented efforts, the patient died intraoperative as a result of cardiac arrest and its complications. Successfully, the newborn survived and it was further investigated to exclude this condition.

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Year:  2013        PMID: 24302663      PMCID: PMC3863017          DOI: 10.1136/bcr-2013-200931

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  18 in total

1.  Aortic valve replacement during pregnancy. A case report and review of the literature.

Authors:  M Ben-Ami; S Battino; T Rosenfeld; G Marin; E Shalev
Journal:  Acta Obstet Gynecol Scand       Date:  1990       Impact factor: 3.636

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5.  Decreased type VI collagen gene expression in cultured Werner's syndrome fibroblasts.

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Journal:  J Invest Dermatol       Date:  1993-06       Impact factor: 8.551

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Journal:  Genomics       Date:  1994-10       Impact factor: 5.736

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Authors:  D Salk
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

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Authors:  M Goto
Journal:  Mech Ageing Dev       Date:  1997-12       Impact factor: 5.432

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Journal:  Adv Exp Med Biol       Date:  1985       Impact factor: 2.622

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Authors:  R A McIvor
Journal:  Int J Cardiol       Date:  1991-07       Impact factor: 4.164

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  1 in total

Review 1.  Research progress on the protective effects of licorice-derived 18β-glycyrrhetinic acid against liver injury.

Authors:  Shou-Yan Wu; Wen-Jie Wang; Jin-Hui Dou; Li-Kun Gong
Journal:  Acta Pharmacol Sin       Date:  2020-03-06       Impact factor: 6.150

  1 in total

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