Literature DB >> 24298517

Hypereosinophilia-an unusual cause of multiple embolic strokes and multi-organ dysfunction.

Geeta A Khwaja1, Ashish Duggal, Amit Kulkarni, Neera Choudhary, Meena Gupta, Debashish Chowdhury, Vikram Bohra, Dhruv Zutshi.   

Abstract

'Eosinophilia' can occur due to a large number of allergic, infectious, neoplastic, and idiopathic diseases. It can range in severity from a self-limiting condition to a life-threatening disorder. The term 'hypereosinophilia' refers to eosinophil levels >1500/μL, and regardless of the underlying cause can be associated with tissue and organ damage. 'Hypereosinophilic syndrome (HES)' is a rare disorder with sustained eosinophilia and multi-organ dysfunction in the absence of a discernable secondary cause. 'Undefined Hypereosinophilic Syndrome' is the most common type of primary hypereosinophilic diseases and we are reporting here one such case who presented with acute multiple embolic strokes secondary to biventricular apical thrombi and multi-organ dysfunction of a fulminant nature. This case highlights the limitation in current diagnostic criteria for HES and emphasizes the need for early intervention.

Entities:  

Keywords:  Encephalopathy; Eosinophilic Myocarditis; Hypereosinophilic Syndrome; Stroke

Year:  2013        PMID: 24298517      PMCID: PMC3843405          DOI: 10.7860/JCDR/2013/6004.3512

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  9 in total

Review 1.  Practical approach to the patient with hypereosinophilia.

Authors:  Florence Roufosse; Peter F Weller
Journal:  J Allergy Clin Immunol       Date:  2010-06-09       Impact factor: 10.793

2.  Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report.

Authors:  Amy D Klion; Bruce S Bochner; Gerald J Gleich; Thomas B Nutman; Marc E Rothenberg; Hans-Uwe Simon; Michael E Wechsler; Peter F Weller
Journal:  J Allergy Clin Immunol       Date:  2006-05-03       Impact factor: 10.793

Review 3.  Eosinophilia.

Authors:  M E Rothenberg
Journal:  N Engl J Med       Date:  1998-05-28       Impact factor: 91.245

4.  Primary restrictive cardiomyopathy. Non-tropical endomyocardial fibrosis and hypereosinophilic heart disease.

Authors:  C Y Chew; G M Ziady; M J Raphael; M Nellen; C M Oakley
Journal:  Br Heart J       Date:  1977-04

Review 5.  The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature.

Authors:  M J Chusid; D C Dale; B C West; S M Wolff
Journal:  Medicine (Baltimore)       Date:  1975-01       Impact factor: 1.889

Review 6.  The idiopathic hypereosinophilic syndrome.

Authors:  P F Weller; G J Bubley
Journal:  Blood       Date:  1994-05-15       Impact factor: 22.113

7.  Neurologic dysfunction in the idiopathic hypereosinophilic syndrome.

Authors:  P M Moore; J B Harley; A S Fauci
Journal:  Ann Intern Med       Date:  1985-01       Impact factor: 25.391

Review 8.  Refining the definition of hypereosinophilic syndrome.

Authors:  Hans-Uwe Simon; Marc E Rothenberg; Bruce S Bochner; Peter F Weller; Andrew J Wardlaw; Michael E Wechsler; Lanny J Rosenwasser; Florence Roufosse; Gerald J Gleich; Amy D Klion
Journal:  J Allergy Clin Immunol       Date:  2010-07       Impact factor: 10.793

9.  Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.

Authors:  Princess U Ogbogu; Bruce S Bochner; Joseph H Butterfield; Gerald J Gleich; Johannes Huss-Marp; Jean Emmanuel Kahn; Kristin M Leiferman; Thomas B Nutman; Florian Pfab; Johannes Ring; Marc E Rothenberg; Florence Roufosse; Marie-Helene Sajous; Javed Sheikh; Dagmar Simon; Hans-Uwe Simon; Miguel L Stein; Andrew Wardlaw; Peter F Weller; Amy D Klion
Journal:  J Allergy Clin Immunol       Date:  2009-12       Impact factor: 10.793

  9 in total
  4 in total

1.  Absolute blood eosinophil count could be a potential biomarker for predicting haemorrhagic transformation after intravenous thrombolysis for acute ischaemic stroke.

Authors:  Neringa Jucevičiūtė; Paulius Mikužis; Renata Balnytė
Journal:  BMC Neurol       Date:  2019-06-13       Impact factor: 2.474

2.  Idiopathic Hypereosinophilic Syndrome Presenting With Embolic Stroke.

Authors:  Magda S Silva; Carina Ramalho; Francelino Ferreira; Inês Maia; Anneke Joosten
Journal:  Cureus       Date:  2021-11-06

Review 3.  Mechanisms and Neuroimaging Patterns of Hypereosinophilia-Related Ischemic Stroke: A Narrative Review through Three Cases.

Authors:  Maria Cristina Cioclu; Francesco Cavallieri; Manuela Napoli; Claudio Moratti; Rosario Pascarella; Franco Valzania; Marialuisa Zedde
Journal:  J Clin Med       Date:  2022-09-23       Impact factor: 4.964

4.  Leukocyte subtypes and adverse clinical outcomes in patients with acute ischemic cerebrovascular events.

Authors:  Anxin Wang; Kehua Quan; Xue Tian; Yingting Zuo; Xia Meng; Pan Chen; Hao Li; Yongjun Wang
Journal:  Ann Transl Med       Date:  2021-05
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.