| Literature DB >> 24298406 |
Jinhee Kwon1, Chang-Yong Lee, Junghwan Oh, Hyun Wook Kang.
Abstract
A balloon-catheter optical diffuser for endometrial treatment was evaluated with computational thermal analysis. Various catheter materials and dimensions were implemented to identify the optimal design for the device. Spatial and temporal development of temperature during 30-sec irradiation of 532-nm light demonstrated thermal insulation effects of polyurethane on temperature increase up to 384 K, facilitating the irreversible denaturation. The current model revealed the degree of thermal coagulation 13% thicker than experimental results possibly due to lack of tissue dynamics and light intensity distribution. In combination with photon distribution, the analytical simulation can be a feasible tool to optimize the new optical diffuser for efficient and safe endometrial treatment.Entities:
Keywords: (000.4430) Numerical approximation and analysis; (120.6810) Thermal effects; (170.1610) Clinical applications; (170.3890) Medical optics instrumentation; (170.4440) ObGyn
Year: 2013 PMID: 24298406 PMCID: PMC3829539 DOI: 10.1364/BOE.4.002450
Source DB: PubMed Journal: Biomed Opt Express ISSN: 2156-7085 Impact factor: 3.732