BACKGROUND: Toxoplasmosis is a common parasitic infection in human around the world and can cause life-threatening encephalitis in human immunodeficiency virus (HIV) infected host. The aim of this study was to assess the frequency of toxoplasma infection in illicit drug users (IDUs) with and without HIV infection in Iran. METHODS: This study was carried out on 84 IDUs (42 HIV positive as case group and 42 HIV negative subjects as control group) from 2008 to 2009. Serum samples were tested for T. gondii IgG antibodies by Enzym linked immunosorbant assay (ELISA). Based on the company brochure kit, the test was defined positive if the antibody titer was 3 IU/ml or more. The data from these two groups were collected and analyzed. RESULTS: The mean age of HIV positive cases was 34.4±8.6 and for HIV negative cases was 35.9±9.3 year. The mean age and distribution of sex in both groups were equal. The frequency of toxoplasma-IgG in HIV positive and HIV negative was 73.8% and 81%, respectively (p=0.19). CONCLUSION: The results show that prevalence of toxoplasmosis infection in the illicit drug users with HIV positive or negative is equal.
BACKGROUND:Toxoplasmosis is a common parasitic infection in human around the world and can cause life-threatening encephalitis in human immunodeficiency virus (HIV) infected host. The aim of this study was to assess the frequency of toxoplasma infection in illicit drug users (IDUs) with and without HIV infection in Iran. METHODS: This study was carried out on 84 IDUs (42 HIV positive as case group and 42 HIV negative subjects as control group) from 2008 to 2009. Serum samples were tested for T. gondii IgG antibodies by Enzym linked immunosorbant assay (ELISA). Based on the company brochure kit, the test was defined positive if the antibody titer was 3 IU/ml or more. The data from these two groups were collected and analyzed. RESULTS: The mean age of HIV positive cases was 34.4±8.6 and for HIV negative cases was 35.9±9.3 year. The mean age and distribution of sex in both groups were equal. The frequency of toxoplasma-IgG in HIV positive and HIV negative was 73.8% and 81%, respectively (p=0.19). CONCLUSION: The results show that prevalence of toxoplasmosis infection in the illicit drug users with HIV positive or negative is equal.
Entities:
Keywords:
HIV; Illicit drug user.; Toxoplasma antibody
Authors: Petr Kodym; Stepánka Hrdá; Ladislav Machala; Hanus Rozsypal; Marie Stanková; Marek Malý Journal: J Eukaryot Microbiol Date: 2006 Impact factor: 3.346
Authors: V Nissapatorn; A Kamarulzaman; I Init; L H Tan; M Rohela; A Norliza; L L Chan; H M Latt; A Khairul Anuar; K F Quek Journal: Med J Malaysia Date: 2002-09