Literature DB >> 24292811

Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis.

S L Peters1, R A Hlady2, J Opavska2, D Klinkebiel3, S J Pirruccello4, G A Talmon4, J G Sharp1, L Wu5, R Jaenisch6, M A Simpson7, A R Karpf2, R Opavsky8.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 24292811     DOI： 10.1038/leu.2013.364

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


× No keyword cloud information.
  15 in total

1.  Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL).

Authors:  Alexey Palamarchuk; Pearlly S Yan; Nicola Zanesi; Linan Wang; Benjamin Rodrigues; Mark Murphy; Veronica Balatti; Arianna Bottoni; Natalya Nazaryan; Hansjuerg Alder; Laura Rassenti; Thomas J Kipps; Michael Freitas; Carlo M Croce; Yuri Pekarsky
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-30       Impact factor: 11.205

2.  Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia.

Authors:  Marta Kulis; Simon Heath; Marina Bibikova; Ana C Queirós; Alba Navarro; Guillem Clot; Alejandra Martínez-Trillos; Giancarlo Castellano; Isabelle Brun-Heath; Magda Pinyol; Sergio Barberán-Soler; Panagiotis Papasaikas; Pedro Jares; Sílvia Beà; Daniel Rico; Simone Ecker; Miriam Rubio; Romina Royo; Vincent Ho; Brandy Klotzle; Lluis Hernández; Laura Conde; Mónica López-Guerra; Dolors Colomer; Neus Villamor; Marta Aymerich; María Rozman; Mónica Bayes; Marta Gut; Josep L Gelpí; Modesto Orozco; Jian-Bing Fan; Víctor Quesada; Xose S Puente; David G Pisano; Alfonso Valencia; Armando López-Guillermo; Ivo Gut; Carlos López-Otín; Elías Campo; José I Martín-Subero
Journal:  Nat Genet       Date:  2012-10-14       Impact factor: 38.330

3.  Dnmt3a is essential for hematopoietic stem cell differentiation.

Authors:  Grant A Challen; Deqiang Sun; Mira Jeong; Min Luo; Jaroslav Jelinek; Jonathan S Berg; Christoph Bock; Aparna Vasanthakumar; Hongcang Gu; Yuanxin Xi; Shoudan Liang; Yue Lu; Gretchen J Darlington; Alexander Meissner; Jean-Pierre J Issa; Lucy A Godley; Wei Li; Margaret A Goodell
Journal:  Nat Genet       Date:  2011-12-04       Impact factor: 38.330

4.  Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis.

Authors:  Ryan A Hlady; Slavomira Novakova; Jana Opavska; David Klinkebiel; Staci L Peters; Juraj Bies; Jay Hannah; Javeed Iqbal; Kristi M Anderson; Hollie M Siebler; Lynette M Smith; Timothy C Greiner; Dhundy Bastola; Shantaram Joshi; Oksana Lockridge; Melanie A Simpson; Dean W Felsher; Kay-Uwe Wagner; Wing C Chan; Judith K Christman; Rene Opavsky
Journal:  J Clin Invest       Date:  2011-12-01       Impact factor: 14.808

5.  Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group.

Authors:  Torsten Haferlach; Alexander Kohlmann; Lothar Wieczorek; Giuseppe Basso; Geertruy Te Kronnie; Marie-Christine Béné; John De Vos; Jesus M Hernández; Wolf-Karsten Hofmann; Ken I Mills; Amanda Gilkes; Sabina Chiaretti; Sheila A Shurtleff; Thomas J Kipps; Laura Z Rassenti; Allen E Yeoh; Peter R Papenhausen; Wei-Min Liu; P Mickey Williams; Robin Foà
Journal:  J Clin Oncol       Date:  2010-04-20       Impact factor: 44.544

6.  Mutational analysis of DNMT3A gene in acute leukemias and common solid cancers.

Authors:  Min S Kim; Yoo R Kim; Nam J Yoo; Sug H Lee
Journal:  APMIS       Date:  2012-07-03       Impact factor: 3.205

7.  Comprehensive methylome map of lineage commitment from haematopoietic progenitors.

Authors:  Hong Ji; Lauren I R Ehrlich; Jun Seita; Peter Murakami; Akiko Doi; Paul Lindau; Hwajin Lee; Martin J Aryee; Rafael A Irizarry; Kitai Kim; Derrick J Rossi; Matthew A Inlay; Thomas Serwold; Holger Karsunky; Lena Ho; George Q Daley; Irving L Weissman; Andrew P Feinberg
Journal:  Nature       Date:  2010-08-15       Impact factor: 49.962

8.  Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.

Authors:  Aparna Vasanthakumar; Janet B Lepore; Matthew H Zegarek; Masha Kocherginsky; Mahi Singh; Elizabeth M Davis; Petra A Link; John Anastasi; Michelle M Le Beau; Adam R Karpf; Lucy A Godley
Journal:  Blood       Date:  2013-01-11       Impact factor: 22.113

9.  Recurrent DNMT3A mutations in patients with myelodysplastic syndromes.

Authors:  M J Walter; L Ding; D Shen; J Shao; M Grillot; M McLellan; R Fulton; H Schmidt; J Kalicki-Veizer; M O'Laughlin; C Kandoth; J Baty; P Westervelt; J F DiPersio; E R Mardis; R K Wilson; T J Ley; T A Graubert
Journal:  Leukemia       Date:  2011-03-18       Impact factor: 11.528

10.  Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.

Authors:  Li Ding; Timothy J Ley; David E Larson; Christopher A Miller; Daniel C Koboldt; John S Welch; Julie K Ritchey; Margaret A Young; Tamara Lamprecht; Michael D McLellan; Joshua F McMichael; John W Wallis; Charles Lu; Dong Shen; Christopher C Harris; David J Dooling; Robert S Fulton; Lucinda L Fulton; Ken Chen; Heather Schmidt; Joelle Kalicki-Veizer; Vincent J Magrini; Lisa Cook; Sean D McGrath; Tammi L Vickery; Michael C Wendl; Sharon Heath; Mark A Watson; Daniel C Link; Michael H Tomasson; William D Shannon; Jacqueline E Payton; Shashikant Kulkarni; Peter Westervelt; Matthew J Walter; Timothy A Graubert; Elaine R Mardis; Richard K Wilson; John F DiPersio
Journal:  Nature       Date:  2012-01-11       Impact factor: 49.962
View more
  22 in total

1.  Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.

Authors:  Staci L Haney; Ryan A Hlady; Jana Opavska; David Klinkebiel; Samuel J Pirruccello; Samikshan Dutta; Kaustubh Datta; Melanie A Simpson; Lizhao Wu; Rene Opavsky
Journal:  Oncogene       Date:  2015-02-02       Impact factor: 9.867

2.  ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in a CLL mouse model.

Authors:  Chi-Ling Chiang; Swagata Goswami; Frank W Frissora; Zhiliang Xie; Pearlly S Yan; Ralf Bundschuh; Logan A Walker; Xiaomeng Huang; Rajeswaran Mani; Xiaokui M Mo; Sivasubramanian Baskar; Christoph Rader; Mitch A Phelps; Guido Marcucci; John C Byrd; L James Lee; Natarajan Muthusamy
Journal:  Blood       Date:  2019-05-31       Impact factor: 22.113

Review 3.  DNA methylation profiles in cancer diagnosis and therapeutics.

Authors:  Yunbao Pan; Guohong Liu; Fuling Zhou; Bojin Su; Yirong Li
Journal:  Clin Exp Med       Date:  2017-07-27       Impact factor: 3.984

4.  Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.

Authors:  Grant A Challen; Deqiang Sun; Allison Mayle; Mira Jeong; Min Luo; Benjamin Rodriguez; Cates Mallaney; Hamza Celik; Liubin Yang; Zheng Xia; Sean Cullen; Jonathan Berg; Yayun Zheng; Gretchen J Darlington; Wei Li; Margaret A Goodell
Journal:  Cell Stem Cell       Date:  2014-08-14       Impact factor: 24.633

5.  Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.

Authors:  Y-I Chang; X You; G Kong; E A Ranheim; J Wang; J Du; Y Liu; Y Zhou; M-J Ryu; J Zhang
Journal:  Leukemia       Date:  2015-03-24       Impact factor: 11.528

6.  Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

Authors:  Allison Mayle; Liubin Yang; Benjamin Rodriguez; Ting Zhou; Edmund Chang; Choladda V Curry; Grant A Challen; Wei Li; David Wheeler; Vivienne I Rebel; Margaret A Goodell
Journal:  Blood       Date:  2015-01-22       Impact factor: 22.113

7.  Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.

Authors:  Anat Biran; Shanye Yin; Helene Kretzmer; Elisa Ten Hacken; Salma Parvin; Fabienne Lucas; Mohamed Uduman; Catherine Gutierrez; Nathan Dangle; Leah Billington; Fara Faye Regis; Laura Z Rassenti; Arman Mohammad; Gabriela Brunsting Hoffmann; Kristen Stevenson; Mei Zheng; Elizabeth Witten; Stacey M Fernandes; Eugen Tausch; Clare Sun; Stephan Stilgenbauer; Jennifer R Brown; Thomas J Kipps; John C Aster; Andreas Gnirke; Donna S Neuberg; Anthony Letai; Lili Wang; Ruben D Carrasco; Alexander Meissner; Catherine J Wu
Journal:  Cancer Res       Date:  2021-10-22       Impact factor: 13.312

8.  Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a.

Authors:  Staci L Haney; G Michael Upchurch; Jana Opavska; David Klinkebiel; Ryan A Hlady; Abhinav Suresh; Samuel J Pirruccello; Vipul Shukla; Runqing Lu; Stefan Costinean; Angie Rizzino; Adam R Karpf; Shantaram Joshi; Patrick Swanson; Rene Opavsky
Journal:  Cell Rep       Date:  2016-04-28       Impact factor: 9.423

9.  Loss of Dnmt3b accelerates MLL-AF9 leukemia progression.

Authors:  Y Zheng; H Zhang; Y Wang; X Li; P Lu; F Dong; Y Pang; S Ma; H Cheng; S Hao; F Tang; W Yuan; X Zhang; T Cheng
Journal:  Leukemia       Date:  2016-05-02       Impact factor: 11.528

Review 10.  Understanding CLL biology through mouse models of human genetics.

Authors:  Elisa Ten Hacken; Catherine J Wu
Journal:  Blood       Date:  2021-12-23       Impact factor: 25.476
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.