Literature DB >> 2428833

An antibody to a peptide specified by an RNA that is complementary to gamma-endorphin mRNA recognizes an opiate receptor.

D J Carr, K L Bost, J E Blalock.   

Abstract

The putative delta-opiate receptor complex has been identified by a new approach which employed an antibody that is directed against a peptide which binds gamma-endorphin and is specified by RNA that is complementary to that of gamma-endorphin mRNA. This antibody competes with beta-endorphin and naloxone for binding sites on the surface of neuroblastoma X glioma NG108-15 hybrid cells. The opiate receptor complex has an apparent molecular weight of 210,000 and is composed of four noncovalently associated subunits with apparent molecular weights of 68,000, 58,000, 45,000 and 30,000.

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Year:  1986        PMID： 2428833     DOI： 10.1016/0165-5728(86)90039-1

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN： 0165-5728            Impact factor:   3.478


  7 in total

1.  The peptide encoded by angiotensin II complementary RNA does not interfere with angiotensin II action.

Authors:  G Guillemette; G Boulay; S Gagnon; R Bosse; E Escher
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

2.  Are the antibodies to a peptide complementary to angiotensin II useful to isolate the angiotensin II receptor?

Authors:  M de Gasparo; S Whitebread; K Einsle; C Heusser
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

3.  Sequence homology between acquired immunodeficiency syndrome virus envelope protein and interleukin 2.

Authors:  W E Reiher; J E Blalock; T K Brunck
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

4.  Is there a relationship between DNA sequences encoding peptide ligands and their receptors?

Authors:  A Goldstein; D L Brutlag
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

5.  Critical evaluation of a theory of molecular recognition using human insulin-like-growth-factor-I fragment 21-40 and its complementary peptide.

Authors:  J Beattie; D J Flint
Journal:  Biochem J       Date:  1992-04-15       Impact factor: 3.857

6.  Purification of an angiotensin II binding protein by using antibodies to a peptide encoded by angiotensin II complementary RNA.

Authors:  T S Elton; L D Dion; K L Bost; S Oparil; J E Blalock
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

7.  NMR study of the possible interaction in solution of angiotensin II with a peptide encoded by angiotensin II complementary RNA.

Authors:  H L Eaton; R E Austin; S W Fesik; S F Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205
  7 in total

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