Literature DB >> 24285816

Absence of an important vaccine and diagnostic target in carriage- and disease-related nontypeable Haemophilus influenzae.

Heidi C Smith-Vaughan1, Anne B Chang, Derek S Sarovich, Robyn L Marsh, Keith Grimwood, Amanda J Leach, Peter S Morris, Erin P Price.   

Abstract

Nontypeable Haemophilus influenzae (NTHi)-associated disease is a major health problem globally. Whole-genome sequence analysis identified the absence of hpd genes encoding Haemophilus protein D in 3 of 16 phylogenetically distinct NTHi isolates. This novel finding is of potential clinical significance, as protein D and hpd represent important NTHi vaccine antigen and diagnostic targets, respectively.

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Year:  2013        PMID： 24285816      PMCID： PMC3910944          DOI： 10.1128/CVI.00632-13

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  11 in total

1.  Respiratory bacterial pathogens in the nasopharynx and lower airways of Australian indigenous children with bronchiectasis.

Authors:  Kim M Hare; Keith Grimwood; Amanda J Leach; Heidi Smith-Vaughan; Paul J Torzillo; Peter S Morris; Anne B Chang
Journal:  J Pediatr       Date:  2010-07-24       Impact factor: 4.406

2.  Modelling of endemic carriage of Haemophilus influenzae in Aboriginal infants in Northern Australia.

Authors:  H C Smith-Vaughan; J McBroom; J D Mathews
Journal:  FEMS Immunol Med Microbiol       Date:  2001-08

3.  Topical ciprofloxin versus topical framycetin-gramicidin-dexamethasone in Australian aboriginal children with recently treated chronic suppurative otitis media: a randomized controlled trial.

Authors:  Amanda Leach; Yvonne Wood; Edna Gadil; Elizabeth Stubbs; Peter Morris
Journal:  Pediatr Infect Dis J       Date:  2008-08       Impact factor: 2.129

4.  Pneumococcal capsular polysaccharides conjugated to protein D for prevention of acute otitis media caused by both Streptococcus pneumoniae and non-typable Haemophilus influenzae: a randomised double-blind efficacy study.

Authors:  Roman Prymula; Pascal Peeters; Viktor Chrobok; Pavla Kriz; Elena Novakova; Eva Kaliskova; Igor Kohl; Patricia Lommel; Jan Poolman; Jean-Paul Prieels; Lode Schuerman
Journal:  Lancet       Date:  2006-03-04       Impact factor: 79.321

5.  Immunological memory and nasopharyngeal carriage in 4-year-old children previously primed and boosted with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) with or without concomitant prophylactic paracetamol.

Authors:  Roman Prymula; Ahsan Habib; Nancy François; Dorota Borys; Lode Schuerman
Journal:  Vaccine       Date:  2013-02-05       Impact factor: 3.641

6.  Single-dose azithromycin versus seven days of amoxycillin in the treatment of acute otitis media in Aboriginal children (AATAAC): a double blind, randomised controlled trial.

Authors:  Peter S Morris; Gaudencio Gadil; Gabrielle B McCallum; Cate A Wilson; Heidi C Smith-Vaughan; Paul Torzillo; Amanda J Leach
Journal:  Med J Aust       Date:  2010-01-04       Impact factor: 7.738

7.  Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays.

Authors:  Michael J Binks; Beth Temple; Lea-Ann Kirkham; Selma P Wiertsema; Eileen M Dunne; Peter C Richmond; Robyn L Marsh; Amanda J Leach; Heidi C Smith-Vaughan
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

8.  Measuring nasal bacterial load and its association with otitis media.

Authors:  Heidi Smith-Vaughan; Roy Byun; Mangala Nadkarni; Nicholas A Jacques; Neil Hunter; Stephen Halpin; Peter S Morris; Amanda J Leach
Journal:  BMC Ear Nose Throat Disord       Date:  2006-05-10

9.  Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer.

Authors:  Talima Pearson; Philip Giffard; Stephen Beckstrom-Sternberg; Raymond Auerbach; Heidie Hornstra; Apichai Tuanyok; Erin P Price; Mindy B Glass; Benjamin Leadem; James S Beckstrom-Sternberg; Gerard J Allan; Jeffrey T Foster; David M Wagner; Richard T Okinaka; Siew Hoon Sim; Ofori Pearson; Zaining Wu; Jean Chang; Rajinder Kaul; Alex R Hoffmaster; Thomas S Brettin; Richard A Robison; Mark Mayo; Jay E Gee; Patrick Tan; Bart J Currie; Paul Keim
Journal:  BMC Biol       Date:  2009-11-18       Impact factor: 7.431

10.  Effects of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D-conjugate vaccine on nasopharyngeal bacterial colonization in young children: a randomized controlled trial.

Authors:  Menno R van den Bergh; Judith Spijkerman; Kristien M Swinnen; Nancy A François; Thierry G Pascal; Dorota Borys; Lode Schuerman; Ed P F Ijzerman; Jacob P Bruin; Arie van der Ende; Reinier H Veenhoven; Elisabeth A M Sanders
Journal:  Clin Infect Dis       Date:  2012-11-01       Impact factor: 9.079
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  17 in total

1.  Complete Deletion of the Fucose Operon in Haemophilus influenzae Is Associated with a Cluster in Multilocus Sequence Analysis-Based Phylogenetic Group II Related to Haemophilus haemolyticus: Implications for Identification and Typing.

Authors:  Camilla de Gier; Lea-Ann S Kirkham; Niels Nørskov-Lauritsen
Journal:  J Clin Microbiol       Date:  2015-09-16       Impact factor: 5.948

2.  Duplex Quantitative PCR Assay for Detection of Haemophilus influenzae That Distinguishes Fucose- and Protein D-Negative Strains.

Authors:  Camilla de Gier; Janessa L Pickering; Peter C Richmond; Ruth B Thornton; Lea-Ann S Kirkham
Journal:  J Clin Microbiol       Date:  2016-06-22       Impact factor: 5.948

Review 3.  Toward making inroads in reducing the disparity of lung health in Australian indigenous and new zealand māori children.

Authors:  Anne B Chang; Robyn L Marsh; John W Upham; Lucas R Hoffman; Heidi Smith-Vaughan; Deborah Holt; Maree Toombs; Catherine Byrnes; Stephanie T Yerkovich; Paul J Torzillo; Kerry-Ann F O'Grady; Keith Grimwood
Journal:  Front Pediatr       Date:  2015-02-13       Impact factor: 3.418

4.  Haemophilus influenzae: using comparative genomics to accurately identify a highly recombinogenic human pathogen.

Authors:  Erin P Price; Derek S Sarovich; Elizabeth Nosworthy; Jemima Beissbarth; Robyn L Marsh; Janessa Pickering; Lea-Ann S Kirkham; Anthony D Keil; Anne B Chang; Heidi C Smith-Vaughan
Journal:  BMC Genomics       Date:  2015-08-27       Impact factor: 3.969

Review 5.  Molecular tools for differentiation of non-typeable Haemophilus influenzae from Haemophilus haemolyticus.

Authors:  Janessa Pickering; Peter C Richmond; Lea-Ann S Kirkham
Journal:  Front Microbiol       Date:  2014-12-02       Impact factor: 5.640

6.  Reduced middle ear infection with non-typeable Haemophilus influenzae, but not Streptococcus pneumoniae, after transition to 10-valent pneumococcal non-typeable H. influenzae protein D conjugate vaccine.

Authors:  Amanda Jane Leach; Christine Wigger; Kim Hare; Vanya Hampton; Jemima Beissbarth; Ross Andrews; Mark Chatfield; Heidi Smith-Vaughan; Peter Stanley Morris
Journal:  BMC Pediatr       Date:  2015-10-19       Impact factor: 2.125

7.  Haemophilus haemolyticus Interaction with Host Cells Is Different to Nontypeable Haemophilus influenzae and Prevents NTHi Association with Epithelial Cells.

Authors:  Janessa L Pickering; Amy Prosser; Karli J Corscadden; Camilla de Gier; Peter C Richmond; Guicheng Zhang; Ruth B Thornton; Lea-Ann S Kirkham
Journal:  Front Cell Infect Microbiol       Date:  2016-05-09       Impact factor: 5.293

8.  The evidence for non-typeable Haemophilus influenzae as a causative agent of childhood pneumonia.

Authors:  Mary P E Slack
Journal:  Pneumonia (Nathan)       Date:  2017-06-25

9.  SPANDx: a genomics pipeline for comparative analysis of large haploid whole genome re-sequencing datasets.

Authors:  Derek S Sarovich; Erin P Price
Journal:  BMC Res Notes       Date:  2014-09-08

Review 10.  Predominant Bacteria Detected from the Middle Ear Fluid of Children Experiencing Otitis Media: A Systematic Review.

Authors:  Chinh C Ngo; Helen M Massa; Ruth B Thornton; Allan W Cripps
Journal:  PLoS One       Date:  2016-03-08       Impact factor: 3.240
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