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Literature DB >> 24283621

Peniciketals A-C, new spiroketals from saline soil derived Penicillium raistrichii.

Wei-Zhong Liu¹, Li-Ying Ma, De-Sheng Liu, Yu-Ling Huang, Chun-Hua Wang, Shou-Sen Shi, Xiao-Hong Pan, Xiao-Dong Song, Rong-Xiu Zhu.

Abstract

Peniciketals A-C (1-3), three new spiroketals with a benzo-fused 2,8-dioxabicyclo[3.3.1]nonane moiety, were isolated from the saline soil derived fungus Penicillium raistrichii. Their structures including absolute configurations were established by NMR, X-ray diffraction, and ECD calculations. Their cytotoxicities were tested against A549, HL-60, and K562 cell lines, and 1-3 showed the selective effects on HL-60 cells with IC50 values of 3.2, 6.7, and 4.5 μM, respectively.

Entities: Chemical Disease Gene

Mesh：

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Year: 2013 PMID： 24283621 DOI： 10.1021/ol403076s

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

7 in total

1. Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

Authors: J Houbraken; S Kocsubé; C M Visagie; N Yilmaz; X-C Wang; M Meijer; B Kraak; V Hubka; K Bensch; R A Samson; J C Frisvad
Journal: Stud Mycol Date: 2020-06-27 Impact factor: 16.097

2. Total Syntheses of (+)-Peniciketals A-B and (-)-Diocollettines A Exploiting a Photoisomerization/Cyclization Union Protocol.

Authors: Yifan Deng; Yike Zou; Chia-Ping H Yang; K N Houk; Amos B Smith
Journal: J Org Chem Date: 2021-09-12 Impact factor: 4.198

Peniciketals A-C, new spiroketals from saline soil derived Penicillium raistrichii.

1. Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

2. Total Syntheses of (+)-Peniciketals A-B and (-)-Diocollettines A Exploiting a Photoisomerization/Cyclization Union Protocol.

3. Enantioselective Total Synthesis of (+)-Peniciketals A and B: Two Architecturally Complex Spiroketals.

4. Sargassopenillines A-G, 6,6-spiroketals from the alga-derived fungi Penicillium thomii and Penicillium lividum.

5. Pyran Rings Containing Polyketides from Penicillium raistrickii.

6. Raistrickiones A-E from a Highly Productive Strain of Penicillium raistrickii Generated through Thermo Change.

Review 7. The Novel Compounds with Biological Activity Derived from Soil Fungi in the Past Decade.