Literature DB >> 24279196

A case for neuroprotection in ophthalmology: developments in translational research.

Andrew J Payne1, Simon Kaja, Nelson R Sabates, Peter Koulen.   

Abstract

Cellular aging occurs by the lifelong accumulation of oxidative damage leading to neuronal apoptosis, termed 'neurodegeneration', and the functional deficits of aging. Loss of visual function is one of the most important quality of life measures for older adults. We discuss recent clinical and laboratory advances in the neuroprotective treatment of the aging eye with particular emphasis on the three major ocular neurodegenerative conditions: glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy (DR).

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Year:  2013        PMID: 24279196      PMCID: PMC3973483     

Source DB:  PubMed          Journal:  Mo Med        ISSN: 0026-6620


  48 in total

1.  Aging: a theory based on free radical and radiation chemistry.

Authors:  D HARMAN
Journal:  J Gerontol       Date:  1956-07

2.  Therapeutic targeting of mitochondrial superoxide in hypertension.

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Review 3.  Consequences of oxidative stress in age-related macular degeneration.

Authors:  Stuart G Jarrett; Michael E Boulton
Journal:  Mol Aspects Med       Date:  2012-04-09

4.  Intracellular mechanisms of N-acylethanolamine-mediated neuroprotection in a rat model of stroke.

Authors:  P Garg; R S Duncan; S Kaja; P Koulen
Journal:  Neuroscience       Date:  2009-12-03       Impact factor: 3.590

5.  Protective effect of epigallocatechin gallate on brain damage after transient middle cerebral artery occlusion in rats.

Authors:  Young Bin Choi; Yeong In Kim; Kwang Soo Lee; Beum Saeng Kim; Dai Jin Kim
Journal:  Brain Res       Date:  2004-09-03       Impact factor: 3.252

Review 6.  Endocannabinoids in the retina: from marijuana to neuroprotection.

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Journal:  Prog Retin Eye Res       Date:  2008-08-03       Impact factor: 21.198

7.  Photodynamic therapy and intravitreal triamcinolone for neovascular age-related macular degeneration: a randomized clinical trial.

Authors:  David Maberley
Journal:  Ophthalmology       Date:  2009-09-12       Impact factor: 12.079

8.  The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium.

Authors:  Prajitha Thampi; Haripriya Vittal Rao; Sayak K Mitter; Jun Cai; Haoyu Mao; Hong Li; Soojung Seo; Xiaoping Qi; Alfred S Lewin; Carl Romano; Michael E Boulton
Journal:  PLoS One       Date:  2012-04-03       Impact factor: 3.240

9.  The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line.

Authors:  R Scott Duncan; Kent D Chapman; Peter Koulen
Journal:  Mol Neurodegener       Date:  2009-12-10       Impact factor: 14.195

10.  Neuroprotective actions of methylene blue and its derivatives.

Authors:  Ethan Poteet; Ali Winters; Liang-Jun Yan; Kyle Shufelt; Kayla N Green; James W Simpkins; Yi Wen; Shao-Hua Yang
Journal:  PLoS One       Date:  2012-10-31       Impact factor: 3.240

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  9 in total

Review 1.  Differential Gene Expression in Age-Related Macular Degeneration.

Authors:  Denise J Morgan; Margaret M DeAngelis
Journal:  Cold Spring Harb Perspect Med       Date:  2014-10-23       Impact factor: 6.915

Review 2.  The role of epigenetics in age-related macular degeneration.

Authors:  M Gemenetzi; A J Lotery
Journal:  Eye (Lond)       Date:  2014-09-19       Impact factor: 3.775

3.  Differential subcellular Ca2+ signaling in a highly specialized subpopulation of astrocytes.

Authors:  Simon Kaja; Andrew J Payne; Krupa R Patel; Yuliya Naumchuk; Peter Koulen
Journal:  Exp Neurol       Date:  2014-12-24       Impact factor: 5.330

Review 4.  The stress response protein REDD1 as a causal factor for oxidative stress in diabetic retinopathy.

Authors:  William P Miller; Siddharth Sunilkumar; Michael D Dennis
Journal:  Free Radic Biol Med       Date:  2021-01-29       Impact factor: 7.376

5.  Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice.

Authors:  Neal D Heuss; Mark J Pierson; Kim Ramil C Montaniel; Scott W McPherson; Ute Lehmann; Stacy A Hussong; Deborah A Ferrington; Walter C Low; Dale S Gregerson
Journal:  J Neuroinflammation       Date:  2014-08-13       Impact factor: 8.322

6.  Plasma Metabolomics of Intermediate and Neovascular Age-Related Macular Degeneration Patients.

Authors:  Sabrina L Mitchell; Chunyu Ma; William K Scott; Anita Agarwal; Margaret A Pericak-Vance; Jonathan L Haines; Dean P Jones; Karan Uppal; Milam A Brantley
Journal:  Cells       Date:  2021-11-12       Impact factor: 6.600

7.  VEGF-B inhibits hyperglycemia- and Macugen-induced retinal apoptosis.

Authors:  Delong Huang; Chen Zhao; Rong Ju; Anil Kumar; Geng Tian; Lijuan Huang; Lei Zheng; Xianglin Li; Lixian Liu; Shasha Wang; Xiangrong Ren; Zhimin Ye; Wei Chen; Liying Xing; Qishan Chen; Zhiqin Gao; Jia Mi; Zhongshu Tang; Bin Wang; Shuping Zhang; Chunsik Lee; Xuri Li
Journal:  Sci Rep       Date:  2016-05-18       Impact factor: 4.379

Review 8.  Cytidine 5'-Diphosphocholine (Citicoline) in Glaucoma: Rationale of Its Use, Current Evidence and Future Perspectives.

Authors:  Gloria Roberti; Lucia Tanga; Manuele Michelessi; Luciano Quaranta; Vincenzo Parisi; Gianluca Manni; Francesco Oddone
Journal:  Int J Mol Sci       Date:  2015-11-30       Impact factor: 5.923

Review 9.  Reactive Oxygen Species-Mediated Damage of Retinal Neurons: Drug Development Targets for Therapies of Chronic Neurodegeneration of the Retina.

Authors:  Landon J Rohowetz; Jacob G Kraus; Peter Koulen
Journal:  Int J Mol Sci       Date:  2018-10-27       Impact factor: 5.923

  9 in total

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