Literature DB >> 24279190

Alzheimer disease: current concepts & future directions.

Erik S Musiek1, Suzanne E Schindler.   

Abstract

Alzheimer disease (AD) is the most common cause of dementia in individuals over age 65, and is expected to cause a major public health crisis as the number of older Americans rapidly expands in the next three decades. Herein, we review current strategies for diagnosis and management of AD, and discuss ongoing clinical research and future therapeutic directions in the battle against this devastating disease.

Entities:  

Mesh：

Year:  2013        PMID： 24279190      PMCID： PMC6179870     

Source DB:  PubMed          Journal:  Mo Med        ISSN： 0026-6620


  20 in total

1.  The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.

Authors:  Guy M McKhann; David S Knopman; Howard Chertkow; Bradley T Hyman; Clifford R Jack; Claudia H Kawas; William E Klunk; Walter J Koroshetz; Jennifer J Manly; Richard Mayeux; Richard C Mohs; John C Morris; Martin N Rossor; Philip Scheltens; Maria C Carrillo; Bill Thies; Sandra Weintraub; Creighton H Phelps
Journal:  Alzheimers Dement       Date:  2011-04-21       Impact factor: 21.566

Review 2.  γ-Secretase inhibitors and modulators for Alzheimer's disease.

Authors:  Michael S Wolfe
Journal:  J Neurochem       Date:  2011-11-28       Impact factor: 5.372

Review 3.  Clinical practice. Early Alzheimer's disease.

Authors:  Richard Mayeux
Journal:  N Engl J Med       Date:  2010-06-10       Impact factor: 91.245

4.  The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment.

Authors:  Ziad S Nasreddine; Natalie A Phillips; Valérie Bédirian; Simon Charbonneau; Victor Whitehead; Isabelle Collin; Jeffrey L Cummings; Howard Chertkow
Journal:  J Am Geriatr Soc       Date:  2005-04       Impact factor: 5.562

Review 5.  Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments.

Authors:  Eric M Reiman; Jessica B S Langbaum; Adam S Fleisher; Richard J Caselli; Kewei Chen; Napatkamon Ayutyanont; Yakeel T Quiroz; Kenneth S Kosik; Francisco Lopera; Pierre N Tariot
Journal:  J Alzheimers Dis       Date:  2011       Impact factor: 4.472

6.  Monoclonal antibodies against β-amyloid (Aβ) for the treatment of Alzheimer's disease: the Aβ target at a crossroads.

Authors:  Francesco Panza; Vincenza Frisardi; Bruno P Imbimbo; Davide Seripa; Vincenzo Solfrizzi; Alberto Pilotto
Journal:  Expert Opin Biol Ther       Date:  2011-04-19       Impact factor: 4.388

7.  Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology.

Authors:  D S Knopman; S T DeKosky; J L Cummings; H Chui; J Corey-Bloom; N Relkin; G W Small; B Miller; J C Stevens
Journal:  Neurology       Date:  2001-05-08       Impact factor: 9.910

8.  Validation of a short Orientation-Memory-Concentration Test of cognitive impairment.

Authors:  R Katzman; T Brown; P Fuld; A Peck; R Schechter; H Schimmel
Journal:  Am J Psychiatry       Date:  1983-06       Impact factor: 18.112

9.  Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network.

Authors:  John C Morris; Paul S Aisen; Randall J Bateman; Tammie L S Benzinger; Nigel J Cairns; Anne M Fagan; Bernardino Ghetti; Alison M Goate; David M Holtzman; William E Klunk; Eric McDade; Daniel S Marcus; Ralph N Martins; Colin L Masters; Richard Mayeux; Angela Oliver; Kimberly Quaid; John M Ringman; Martin N Rossor; Stephen Salloway; Peter R Schofield; Natalie J Selsor; Reisa A Sperling; Michael W Weiner; Chengjie Xiong; Krista L Moulder; Virginia D Buckles
Journal:  Clin Investig (Lond)       Date:  2012-10-01

Review 10.  Neuronal nicotinic acetylcholine receptors - targets for the development of drugs to treat cognitive impairment associated with schizophrenia and Alzheimer's disease.

Authors:  Simon N Haydar; John Dunlop
Journal:  Curr Top Med Chem       Date:  2010       Impact factor: 3.295
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  7 in total

1.  Reversible Pharmacological Induction of Motor Symptoms in MPTP-Treated Mice at the Presymptomatic Stage of Parkinsonism: Potential Use for Early Diagnosis of Parkinson's Disease.

Authors:  Gulnara R Khakimova; Elena A Kozina; Valerian G Kucheryanu; Michael V Ugrumov
Journal:  Mol Neurobiol       Date:  2016-05-19       Impact factor: 5.590

Review 2.  Over-Prescribed Medications, Under-Appreciated Risks: A Review of the Cognitive Effects of Anticholinergic Medications in Older Adults.

Authors:  Daniel M I Britt; Gregory S Day
Journal:  Mo Med       Date:  2016 May-Jun

3.  Dopamine induces the accumulation of insoluble prion protein and affects autophagic flux.

Authors:  Marcio H M da Luz; Italo T Peres; Tiago G Santos; Vilma R Martins; Marcelo Y Icimoto; Kil S Lee
Journal:  Front Cell Neurosci       Date:  2015-02-02       Impact factor: 5.505

4.  Finding Potent Sirt Inhibitor in Coffee: Isolation, Confirmation and Synthesis of Javamide-II (N-Caffeoyltryptophan) as Sirt1/2 Inhibitor.

Authors:  Jae B Park
Journal:  PLoS One       Date:  2016-03-17       Impact factor: 3.240

Review 5.  Alzheimer's Disease, Inflammation, and the Role of Antioxidants.

Authors:  Benjamin Sinyor; Jocelyn Mineo; Christopher Ochner
Journal:  J Alzheimers Dis Rep       Date:  2020-06-16

Review 6.  Dysfunctional Glucose Metabolism in Alzheimer's Disease Onset and Potential Pharmacological Interventions.

Authors:  Vijay Kumar; So-Hyeon Kim; Kausik Bishayee
Journal:  Int J Mol Sci       Date:  2022-08-23       Impact factor: 6.208

Review 7.  Machine learning for modeling the progression of Alzheimer disease dementia using clinical data: a systematic literature review.

Authors:  Sayantan Kumar; Inez Oh; Suzanne Schindler; Albert M Lai; Philip R O Payne; Aditi Gupta
Journal:  JAMIA Open       Date:  2021-08-02
  7 in total

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