Literature DB >> 24273853

Pulchranins B and C, new acyclic guanidine alkaloids from the Far-Eastern marine sponge Monanchora pulchra.

Tatyana N Makarieva1, Ekaterina K Ogurtsova, Yuliya V Korolkova, Yaroslav A Andreev, Irina V Mosharova, Ksenya M Tabakmakher, Alla G Guzii, Vladimir A Denisenko, Pavel S Dmitrenok, Hyi-Seung Lee, Eugene V Grishin, Valentin A Stonik.   

Abstract

New marine natural products, pulchranins B and C (2 and 3), were isolated from the marine sponge Monanchora pulchra and their structures were established using NMR and MS analysis. Compounds 2 and 3 were moderately active as inhibitors of TRPV1 (EC50 value of 95 and 183 microM, respectively) and less potent against TRPV3 and TRPA1 receptors.

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Year:  2013        PMID: 24273853

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN: 1555-9475            Impact factor:   0.986


  4 in total

Review 1.  Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas.

Authors:  Amr El-Demerdash; Atanas G Atanasov; Anupam Bishayee; Mamdouh Abdel-Mogib; John N A Hooper; Ali Al-Mourabit
Journal:  Nutrients       Date:  2018-01-02       Impact factor: 5.717

2.  TRPV1 activation power can switch an action mode for its polypeptide ligands.

Authors:  Maxim V Nikolaev; Natalia A Dorofeeva; Margarita S Komarova; Yuliya V Korolkova; Yaroslav A Andreev; Irina V Mosharova; Eugene V Grishin; Denis B Tikhonov; Sergey A Kozlov
Journal:  PLoS One       Date:  2017-05-05       Impact factor: 3.240

3.  Marine Cyclic Guanidine Alkaloids Monanchomycalin B and Urupocidin A Act as Inhibitors of TRPV1, TRPV2 and TRPV3, but not TRPA1 Receptors.

Authors:  Yuliya Korolkova; Tatyana Makarieva; Kseniya Tabakmakher; Larisa Shubina; Ekaterina Kudryashova; Yaroslav Andreev; Irina Mosharova; Hyi-Seung Lee; Yeon-Ju Lee; Sergey Kozlov
Journal:  Mar Drugs       Date:  2017-03-23       Impact factor: 5.118

Review 4.  Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids.

Authors:  Jin Liu; Xu-Wen Li; Yue-Wei Guo
Journal:  Mar Drugs       Date:  2017-10-24       Impact factor: 5.118

  4 in total

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