| Literature DB >> 24272695 |
J D McChesney1, M Gonzalez-Sierra.
Abstract
Several 6-chloro-5-nitropyrimidines were synthesized, and their antifungal activity was tested. Some derivatives were equipotent or superior to amphotericin B in vitro but their relatively high toxicity in mice and their chemical instability discourage further evaluation.Entities:
Year: 1985 PMID： 24272695 DOI： 10.1023/A:1016323702665
Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200