Literature DB >> 2427097

Desensitization of iloprost responsiveness in human platelets follows prolonged exposure to iloprost in vitro.

U Alt, P J Leigh, A J Wilkins, P K Morris, J MacDermot.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 2427097      PMCID： PMC1401073     

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


× No keyword cloud information.
  3 in total

1.  Evidence for distinct prostaglandin I2 and D2 receptors in human platelets.

Authors:  O V Miller; R R Gorman
Journal:  J Pharmacol Exp Ther       Date:  1979-07       Impact factor: 4.030

2.  Decreased sensitivity of human platelets to PGI2 during long-term intraarterial prostacyclin infusion in patients with peripheral vascular disease--a rebound phenomenon?

Authors:  H Sinzinger; K Silberbauer; A K Horsch; A Gall
Journal:  Prostaglandins       Date:  1981-01

3.  Desensitization of prostacyclin responsiveness in a neuronal hybrid cell line: selective loss of high affinity receptors.

Authors:  P J Leigh; J MacDermot
Journal:  Br J Pharmacol       Date:  1985-05       Impact factor: 8.739
  3 in total
  8 in total

1.  Internalization and down-regulation of the prostacyclin receptor in human platelets.

Authors:  S Giovanazzi; M R Accomazzo; O Letari; D Oliva; S Nicosia
Journal:  Biochem J       Date:  1997-07-01       Impact factor: 3.857

2.  The effect of iloprost on the ADP-ribosylation of Gs alpha (the alpha-subunit of Gs).

Authors:  L Molina y Vedia; R D Nolan; E G Lapetina
Journal:  Biochem J       Date:  1989-08-01       Impact factor: 3.857

3.  Iloprost-induced translocation of a 23-kDa protein that is recognized by a Gs alpha antiserum.

Authors:  L Molina Y Vedia; E G Lapetina
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

4.  Prostacyclin-dependent cyclic AMP formation in endothelial cells.

Authors:  H Schröder; K Schrör
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-01       Impact factor: 3.000

5.  Iloprost antagonizes the increase in internal calcium concentration induced by alpha-thrombin in human platelets: a study of desensitization.

Authors:  E Cecchi; L Capone; C Ruocco; A Fazzini; A Mugelli; A Giotti; P Failli
Journal:  Cardiovasc Drugs Ther       Date:  1995-12       Impact factor: 3.727

Review 6.  Iloprost. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in peripheral vascular disease, myocardial ischaemia and extracorporeal circulation procedures.

Authors:  S M Grant; K L Goa
Journal:  Drugs       Date:  1992-06       Impact factor: 9.546

7.  Acute reduction of TxA2 platelet binding sites after in vivo administration of a TxA2 receptor inhibitor.

Authors:  P A Modesti; A Colella; I Cecioni; G F Gensini; R Abbate; G G Neri Serneri
Journal:  Br J Clin Pharmacol       Date:  1991-04       Impact factor: 4.335

8.  Prostacyclin analogues reduce ADP-ribosylation of the alpha-subunit of the regulatory Gs-protein and diminish adenosine (A2) responsiveness of platelets.

Authors:  R J Edwards; J MacDermot; A J Wilkins
Journal:  Br J Pharmacol       Date:  1987-03       Impact factor: 8.739
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.