Literature DB >> 2427072

Regulation of concentrations of mRNA for amylase, trypsinogen I and chymotrypsinogen B in rat pancreas by secretagogues.

W Renaud, D Giorgi, J Iovanna, J C Dagorn.   

Abstract

Regulation of pancreatic gene expression by the secretory stimulants cholecystokinin-pancreozymin, caerulein and pilocarpine was studied in the rat, by using cloned cDNA probes to quantify concentrations of specific mRNAs (amylase, trypsinogen I and chymotrypsinogen B). It is concluded that long-term pancreatic stimulation results in pre-translational regulation of secretory-protein gene expression, with a preferential accumulation of RNA transcripts encoding serine proteinases, compared with that for amylase.

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Year:  1986        PMID： 2427072      PMCID： PMC1146683          DOI： 10.1042/bj2350305

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  20 in total

1.  A modified spectrophotometric determination of chymotrypsin, trypsin, and thrombin.

Authors:  B C HUMMEL
Journal:  Can J Biochem Physiol       Date:  1959-12

2.  Methylmercury as a reversible denaturing agent for agarose gel electrophoresis.

Authors:  J M Bailey; N Davidson
Journal:  Anal Biochem       Date:  1976-01       Impact factor: 3.365

3.  Different action of hormonal stimulation on the biosynthesis of three pancreatic enzymes.

Authors:  J C Dagorn; R Mongeau
Journal:  Biochim Biophys Acta       Date:  1977-06-23

4.  Nutritional and hormonal effects on RNA polymerase enzyme activities in pancreas.

Authors:  O Black; P D Webster
Journal:  Am J Physiol       Date:  1974-12

Review 5.  The neurohumoral control of pancreatic exocrine secretion.

Authors:  F P Brooks
Journal:  Am J Clin Nutr       Date:  1973-03       Impact factor: 7.045

6.  [Adaptation of the rate of biosynthesis of pancreatic amylase and chymotrypsinogen A to starch-rich or protein-rich diets].

Authors:  J P Reboud; G Marchis-Mouren; L Paséro; A Cozzone; P Desnuelle
Journal:  Biochim Biophys Acta       Date:  1966-04-25

7.  Effect of chronic pentagastrin, cholecystokinin, and secretin on pancreas of rats.

Authors:  H Petersen; T Solomon; M I Grossman
Journal:  Am J Physiol       Date:  1978-03

8.  Hormonal control of pancreatic growth.

Authors:  D L Mainz; O Black; P D Webster
Journal:  J Clin Invest       Date:  1973-09       Impact factor: 14.808

9.  Nucleotide sequence of the rightward operator of phage lambda.

Authors:  T Maniatis; A Jeffrey; D G Kleid
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

10.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors:  J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal:  Biochemistry       Date:  1979-11-27       Impact factor: 3.162
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  6 in total

1.  Characterization of secretory responses in exocrine pancreas of genetically obese Zucker rats.

Authors:  Y Habara; A Uehara; Y Takasugi; M Namiki; T Kanno
Journal:  Int J Pancreatol       Date:  1991 Nov-Dec

Review 2.  Regulation of gene expression in pancreatic adaptation to nutritional substrates or hormones.

Authors:  H F Kern; U Rausch; G A Scheele
Journal:  Gut       Date:  1987       Impact factor: 23.059

3.  Increase in pancreatic lipase and trypsin activity and their mRNA levels in streptozotocin-induced diabetic rats.

Authors:  R D Duan; J Poensgen; C Wicker; B Weström; C Erlanson-Albertsson
Journal:  Dig Dis Sci       Date:  1989-08       Impact factor: 3.199

4.  Effects of secretin and caerulein on enzymes of cultured pancreatic acinar cells.

Authors:  K K Hirschi; S Kenny; J D Justice; P M Brannon
Journal:  In Vitro Cell Dev Biol       Date:  1991-08

5.  Translational control of anionic trypsinogen and amylase synthesis in rat pancreas in response to caerulein stimulation.

Authors:  W Steinhilber; J Poensgen; U Rausch; H F Kern; G A Scheele
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

6.  Caerulein and gastrin(2-17 ds) regulate differently synthesis of secretory enzymes, mRNA levels and cell proliferation in pancreatic acinar cells (AR4-2J).

Authors:  P Pradel; A Estival; C Seva; C Wicker-Planquart; A Puigserver; N Vaysse; F Clemente
Journal:  Biochem J       Date:  1993-02-15       Impact factor: 3.857
  6 in total

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