Literature DB >> 24270503

Covering your bases: inheritance of DNA methylation in plant genomes.

Chad E Niederhuth1, Robert J Schmitz.   

Abstract

Cytosine methylation is an important base modification that is inherited across mitotic and meiotic cell divisions in plant genomes. Heritable methylation variants can contribute to within-species phenotypic variation. Few methylation variants were known until recently, making it possible to begin to address major unanswered questions: the extent of natural methylation variation within plant genomes, its effects on phenotypic variation, its degree of dependence on genotype, and how it fits into an evolutionary context. Techniques like whole-genome bisulfite sequencing (WGBS) make it possible to determine cytosine methylation states at single-base resolution across entire genomes and populations. Application of this method to natural and novel experimental populations is revealing answers to these long-standing questions about the role of DNA methylation in plant genomes.

Entities:  

Keywords:  DNA methylation; epiallele; epigenetics; whole-genome bisulfite sequencing.

Mesh:

Substances:

Year:  2013        PMID: 24270503      PMCID: PMC3941479          DOI: 10.1093/mp/sst165

Source DB:  PubMed          Journal:  Mol Plant        ISSN: 1674-2052            Impact factor:   13.164


  72 in total

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Authors:  Robert J Schmitz; Matthew D Schultz; Mathew G Lewsey; Ronan C O'Malley; Mark A Urich; Ondrej Libiger; Nicholas J Schork; Joseph R Ecker
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Journal:  Plant Cell       Date:  2013-08-06       Impact factor: 11.277

10.  Arabidopsis PAI gene arrangements, cytosine methylation and expression.

Authors:  S Melquist; B Luff; J Bender
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4.  Major Domestication-Related Phenotypes in Indica Rice Are Due to Loss of miRNA-Mediated Laccase Silencing.

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Review 7.  Genetic Improvement in Sunflower Breeding-Integrated Omics Approach.

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9.  Widespread natural variation of DNA methylation within angiosperms.

Authors:  Chad E Niederhuth; Adam J Bewick; Lexiang Ji; Magdy S Alabady; Kyung Do Kim; Qing Li; Nicholas A Rohr; Aditi Rambani; John M Burke; Joshua A Udall; Chiedozie Egesi; Jeremy Schmutz; Jane Grimwood; Scott A Jackson; Nathan M Springer; Robert J Schmitz
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10.  A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation.

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