Amr M El Khouli1, Enas Ahmed El-Gendy2. 1. Associate Professor of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Faculty of Dentistry, October 6 University, 6th of October City, Egypt. Electronic address: amrelkhouli@hotmail.com. 2. Lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Faculty of Dentistry, October 6 University, 6th of October City, Egypt.
Abstract
OBJECTIVE: This study assessed the effects of systemic omega-3 on the treatment of recurrent aphthous stomatitis and on the improvement of quality of life. STUDY DESIGN:Fifty participants were randomly assigned to receive either omega-3 (1 g, 3 times daily) or placebo for 6 months. Assessment of outcome measures including monthly number of new ulcers, average duration of ulcer episodes, and pain level of ulcers was carried out at baseline and monthly for 6 months. Analysis of potential impact on quality of life using the Oral Health Impact Profile 14 was carried out at baseline and 6 months. RESULTS: Daily omega-3 treatment achieved a significant reduction in number of ulcers, duration of ulcers, and level of pain by 3 months that persisted for 6 months. Mean score on Oral Health Impact Profile 14 also significantly improved by 6 months. CONCLUSIONS: A daily omega-3 regimen shows promise as therapy for treatment and management of patients with recurrent aphthous stomatitis.
RCT Entities:
OBJECTIVE: This study assessed the effects of systemic omega-3 on the treatment of recurrent aphthous stomatitis and on the improvement of quality of life. STUDY DESIGN: Fifty participants were randomly assigned to receive either omega-3 (1 g, 3 times daily) or placebo for 6 months. Assessment of outcome measures including monthly number of new ulcers, average duration of ulcer episodes, and pain level of ulcers was carried out at baseline and monthly for 6 months. Analysis of potential impact on quality of life using the Oral Health Impact Profile 14 was carried out at baseline and 6 months. RESULTS: Daily omega-3 treatment achieved a significant reduction in number of ulcers, duration of ulcers, and level of pain by 3 months that persisted for 6 months. Mean score on Oral Health Impact Profile 14 also significantly improved by 6 months. CONCLUSIONS: A daily omega-3 regimen shows promise as therapy for treatment and management of patients with recurrent aphthous stomatitis.
Authors: Mohammed Khaleel Ahmed; Mohammed Jafer; Maryam Nayeem; Ibtisam Hussain Moafa; Mir Furruq Ali Quadri; Hema Gopalaiah; Mir Faeq Ali Quadri Journal: J Multidiscip Healthc Date: 2020-11-18