Antigenic polymorphism of a serum protein migrating electrophoretically in the alpha region detected by using a strain derived from the Japanese wild mouse (Mus musculus molossinus).

Antigenic specificities of a serum protein from the mouse Mol-A strain (a strain derived from the Japanese wild mouse, Mus musculus molossinus) was studied by gel precipitation with alloantisera produced by reciprocal alloimmunization between Mol-A and BALB/c mice. Alloantigens which migrate immunoelectrophoretically in the alpha region of serum proteins have also been identified. The evidence indicated that this antigenic specificity is controlled by a codominant autosomal locus designated Aph-1. The evidence also suggests that the Aph-1 locus is linked to the alpha locus on chromosome 2.