Literature DB >> 24255988

Pancreaticoduodenectomy--the transition from a low- to a high-volume center.

Daniel Ansari1, Caroline Williamsson, Bobby Tingstedt, Bodil Andersson, Gert Lindell, Roland Andersson.   

Abstract

OBJECTIVE: Previous studies have identified a significant volume-outcome relationship for hospitals performing pancreaticoduodenectomy (PD). However, scant information exists concerning the effects of increased caseload of PD within the same hospital. Here, we describe the effects of becoming a high-volume provider of PD.
MATERIAL AND METHODS: The study group comprised 221 patients who underwent PD between 2000 and 2012. Hospital volume was allocated into three groups: low-volume (<10 PDs/year), years 2000-2004, n = 25; medium-volume (10-24 PDs/year), years 2005-2009, n = 86; and high-volume (≥25 PDs/year), years 2010-2012, n = 110.
RESULTS: The annual number of PDs increased from 5 in 2000 to 39 in 2012. The median operative duration decreased over the volume categories (p < 0.001). Intraoperative blood loss dropped (p < 0.001). The need for intraoperative blood transfusion was reduced (p < 0.001). Increasing hospital volume was associated with fewer reoperations (p = 0.041) and shorter postoperative length of stay (p = 0.010). There was a tendency toward reduced mortality: 4.0% for the low-volume period, 2.3% for the medium-volume period, and 0% for the high-volume period (p = 0.066).
CONCLUSIONS: The transition from a low- to a high-volume center resulted in optimized outcomes for PD and 0% operative mortality, favoring the continued centralization of this high-risk operation.

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Year:  2013        PMID: 24255988     DOI: 10.3109/00365521.2013.847116

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN: 0036-5521            Impact factor:   2.423


  5 in total

Review 1.  Update on the management of pancreatic cancer: surgery is not enough.

Authors:  Daniel Ansari; Adam Gustafsson; Roland Andersson
Journal:  World J Gastroenterol       Date:  2015-03-21       Impact factor: 5.742

2.  The Impact of Increasing Hospital Volume on 90-Day Postoperative Outcomes Following Pancreaticoduodenectomy.

Authors:  Daniel J Kagedan; Nik Goyert; Qing Li; Lawrence Paszat; Alexander Kiss; Craig C Earle; Paul J Karanicolas; Alice C Wei; Nicole Mittmann; Natalie G Coburn
Journal:  J Gastrointest Surg       Date:  2017-01-05       Impact factor: 3.452

Review 3.  Obesity and Pancreatic Cancer: Overview of Epidemiology and Potential Prevention by Weight Loss.

Authors:  Mu Xu; Xiaoman Jung; O Joe Hines; Guido Eibl; Yijun Chen
Journal:  Pancreas       Date:  2018-02       Impact factor: 3.327

4.  Outcome and evaluation of prognostic factors after pancreaticoduodenectomy for distal cholangiocarcinoma.

Authors:  Johannes Byrling; Roland Andersson; Agata Sasor; Gert Lindell; Daniel Ansari; Johan Nilsson; Bodil Andersson
Journal:  Ann Gastroenterol       Date:  2017-06-20

5.  Outcome after implementation of a clinical pathway for pancreaticoduodenectomy in a low volume centre.

Authors:  Thomas Zacharias; Dan Sebastien; Ferreira Nelio
Journal:  Contemp Oncol (Pozn)       Date:  2022-06-20
  5 in total

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